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Piperidolate

Piperidolate structure

Piperidolate 

structure
  • CAS No:

    82-98-4

  • Formula:

    C21H25NO2

  • Chemical Name:

    Piperidolate

  • Synonyms:

    Benzeneacetic acid,α-phenyl-,1-ethyl-3-piperidinyl ester;Acetic acid,diphenyl-,1-ethyl-3-piperidyl ester;3-Piperidinol,1-ethyl-,diphenylacetate (ester);JB 305;1087 A.N.;N-Ethyl-3-piperidyl diphenylacetate;1-Ethyl-3-piperidyl diphenylacetate;Piperidolate;Dactil;1-Ethylpiperidin-3-yl 2,2-diphenylacetate

Description

Piperidolate is an antimuscarinic, inhibits intestinal cramp induced by acetylcholine (rats and dogs).


2,2-diphenylacetic acid (1-ethyl-3-piperidinyl) ester is a diarylmethane.

Piperidolate Basic Attributes

323.436

323.43

201-449-7

DTXSID7048164

A - Alimentary tract and metabolism

2933399090

Characteristics

29.5

4.44

1.1±0.1 g/cm3

<25 °C

191 °C

136.0±19.6 °C

1.584

LD50 intravenous in guinea pig: 16mg/kg

Safety Information

36/37/39-45

T

P261, P264, P270, P271, P280, P301+P310, P302+P352, P304+P340, P311, P312, P321, P322, P330, P361, P363, P403+P233, P405, P501

H301

|Danger|H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P310, P302+P352, P304+P340, P311, P312, P321, P322, P330, P361, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

N-ethyl-3-piperidyl diphenylacetate

Piperidolate Use and Manufacturing

Pharmaceuticals

Computed Properties

Molecular Weight:323.4
XLogP3:4.4
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:323.188529040
Monoisotopic Mass:323.188529040
Topological Polar Surface Area:29.5
Heavy Atom Count:24
Complexity:367
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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