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Hymenialdisine

Hymenialdisine structure

Hymenialdisine 

structure
  • CAS No:

    82005-12-7

  • Formula:

    C11H10BrN5O2

  • Chemical Name:

    Hymenialdisine

  • Synonyms:

    Pyrrolo[2,3-c]azepin-8(1H)-one,4-(2-amino-1,5-dihydro-5-oxo-4H-imidazol-4-ylidene)-2-bromo-4,5,6,7-tetrahydro-,(4Z)-;Pyrrolo[2,3-c]azepin-8(1H)-one,4-(2-amino-1,5-dihydro-5-oxo-4H-imidazol-4-ylidene)-2-bromo-4,5,6,7-tetrahydro-,(Z)-;(4Z)-4-(2-Amino-1,5-dihydro-5-oxo-4H-imidazol-4-ylidene)-2-bromo-4,5,6,7-tetrahydropyrrolo[2,3-c]azepin-8(1H)-one;Hymenialdisine;(Z)-Hymenialdisine;Hymenialdesine;Z-Hymenialdisine;10Z-Hymenialdisine;10Z-Hymenialdisine;84094-93-9

Description

Light Yellow Solid

Hymenialdisine Basic Attributes

324.13300

324.13

5WMS4GA67M

626158|607173

Characteristics

112.37000

0.85980

Light Yellow Solid

2.2 g/cm3

160-164ºC

1.911

Drug Information

hymenialdisine

Hymenialdisine Use and Manufacturing

A potent inhibitor of a variety of kinases including MEK-1, GSK-3, and CKI. It also exhibits inhibition of the G2 cell cycle checkpoint at the micromolar concentrations. A marine sponge alkaloid, a natural product

Computed Properties

Molecular Weight:324.13
XLogP3:-0.7
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:3
Exact Mass:323.00179
Monoisotopic Mass:323.00179
Topological Polar Surface Area:112
Heavy Atom Count:19
Complexity:515
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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