10Z-HYMENIALDISINE
-
10Z-HYMENIALDISINE
structure -
-
CAS No:
82005-12-7
-
Formula:
C11H10BrN5O2
-
Chemical Name:
10Z-HYMENIALDISINE
-
Synonyms:
HYMENIALDISINE;HD;(4Z)-4-(2-Amino-1,5-dihydro-5-oxo-4H-imidazol-4-ylidene)-2-bromo-4,5,6,7-tetrahydro-pyrrolo[2,3-c]azepin-8(1H)-one;(Z)-Hymenialdisine;4-(2-AMINO-4-OXO-2-IMIDAZOLIDIN-5-YLIDENE)-2-BROMO-4,5,6,7-TETRAHYDROPYRROLO[2,3-C]AZEPIN-8-ONE;10Z-HYMENIALDISINE;Hymenialdesine;ANTI-HD antibody produced in mouse
-
CAS No:
Characteristics
112.37000
0.85980
Light Yellow Solid
2.20±0.1 g/cm3(Predicted)
160-164ºC
1.911
9.86±0.20(Predicted)
-20°C
10Z-HYMENIALDISINE Use and Manufacturing
A potent inhibitor of a variety of kinases including MEK-1, GSK-3, and CKI. It also exhibits inhibition of the G2 cell cycle checkpoint at the micromolar concentrations. A marine sponge alkaloid, a natural product
Computed Properties
Molecular Weight:324.13
XLogP3:-0.7
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:3
Exact Mass:323.00179
Monoisotopic Mass:323.00179
Topological Polar Surface Area:112
Heavy Atom Count:19
Complexity:515
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes