3,6-Acridinediamine, hydrochloride (1:1)
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3,6-Acridinediamine, hydrochloride (1:1)
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CAS No:
952-23-8
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Formula:
C13H11N3.ClH
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Chemical Name:
3,6-Acridinediamine, hydrochloride (1:1)
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Synonyms:
3,6-Acridinediamine,hydrochloride (1:1);Acridine,3,6-diamino-,monohydrochloride;3,6-Acridinediamine,monohydrochloride;Proflavine monohydrochloride;3,6-Diaminoacridinium chloride;Proflavine hydrochloride;3,6-Diaminoacridine monohydrochloride;NSC 605756
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CAS No:
Description
ChEBI: A hydrochloride resulting from the reaction of equimolar amounts of 3,6-diaminoacridine and hydrogen chloride.
Proflavine hydrochloride is a brown powder. (NTP, 1992)
Proflavine hydrochloride is a brown powder. (NTP, 1992)|3,6-diaminoacridine monohydrochloride is a hydrochloride resulting from the reaction of equimolar amounts of 3,6-diaminoacridine and hydrogen chloride. It has a role as an antibacterial agent, an antiseptic drug, an intercalator and a carcinogenic agent. It contains a 3,6-diaminoacridine(1+).
3,6-Acridinediamine, hydrochloride (1:1) Basic Attributes
245.71
245.071976
213-459-9
51AA3SI0JM
605756
DTXSID8021191
2933990090
Characteristics
64.93000
4.51680
Proflavine hydrochloride is a brown powder. (NTP, 1992)
1.346g/cm3
270°C (dec.) (lit.)
506.9ºC at 760mmHg
292.9ºC
5 to 10 mg/mL at 68° F (NTP, 1992)
Slightly soluble in water.
Amines, Phosphines, and Pyridines
PROFLAVINE HYDROCHLORIDE is amphoteric. Reacts both as a weak acid and as a weak base.
Safety Information
3
R40
AR9064000
|Warning|H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]|P264, P280, P305+P351+P338, and P337+P313|Aggregated GHS information provided by 41 companies from 2 notifications to the ECHA C&L Inventory.
This compound is not very flammable but any fire involving this compound may produce dangerous vapors. You should evacuate the area. All firefighters should wear full-body protective clothing and use self-contained breathing apparatuses. You should extinguish any fires involving this chemical with a dry chemical, carbon dioxide, foam, or halon extinguisher. (NTP, 1992)
SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a strong soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. STORAGE PRECAUTIONS: You should protect this material from exposure to light, and store it in a refrigerator. (NTP, 1992)
RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. RECOMMENDED GLOVE MATERIALS: Permeation data indicate that nitrile gloves may provide protection to contact with this compound. Nitrile over latex gloves is recommended. However, if this chemical makes contact with your gloves, or if a tear, hole or puncture develops, remove them at once. (NTP, 1992)
Drug Information
SYMPTOMS: Irritation to gastrointestinal mucosa resulting in nausea and vomiting. Jaundice and acute toxic hepatitis. ACUTE/CHRONIC HAZARDS: Moderately toxic. May cause irritation on contact. Hazardous decomposition products. (NTP, 1992)
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)
Computed Properties
Molecular Weight:245.71
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Exact Mass:245.0719751
Monoisotopic Mass:245.0719751
Topological Polar Surface Area:64.9
Heavy Atom Count:17
Complexity:232
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
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3,6-Acridinediamine, hydrochloride (1:1)
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