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Home > Encyclopedia > Dihydrocoenzyme Q10

Dihydrocoenzyme Q10

Dihydrocoenzyme Q10 structure

Dihydrocoenzyme Q10 

structure
  • CAS No:

    992-78-9

  • Formula:

    C59H92O4

  • Chemical Name:

    Dihydrocoenzyme Q10

  • Synonyms:

    1,4-Benzenediol,2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaen-1-yl]-5,6-dimethoxy-3-methyl-;Hydroquinone,2-(3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl)-5,6-dimethoxy-3-methyl-;1,4-Benzenediol,2-(3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl)-5,6-dimethoxy-3-methyl-,(all-E)-;1,4-Benzenediol,2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl]-5,6-dimethoxy-3-methyl-;2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-Decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaen-1-yl]-5,6-dimethoxy-3-methyl-1,4-benzenediol;Coenzyme Q10,dihydro-;Coenzyme Q10-hydroquinone;Ubiquinol 50;Reduced coenzyme Q10;Dihydrocoenzyme Q10;Reduced ubiquinone Q10;Kaneka QH;Ubidecarenol;30291-37-3

  • Categories:

    Active Pharmaceutical Ingredients  >  Hormones and the Endocrine System

Description

Ubiquinol (Ubiquinol-10) is a reduced form of coenzyme Q10 (CoQ10). Ubiquinol is a potent antioxidant that has the capacity to protect Vitamin E, and also helps to regenerate depleted vitamin E and Vitamin C. Ubiquinol is both lipophilic and hydrophilic and acts as transmembrane factor preventing lipid peroxidation and propagation by transferring electrons to ROS[1][2][3].


Solid


Ubiquinol-10 is a ubiquinol in which the polyprenyl substituent is decaprenyl. It has a role as a metabolite and a biomarker. It is a polyprenylhydroquinone and an ubiquinol.|Ubiquinol (CoQH2) is a reduced form of coenzyme Q10 (CoQ10) that acts as an active antioxidant that prevents the initiation and propagation of lipid peroxidation in biological membranes and human low-density lipoprotein (LDL). It plays an essential role in maintaining cellular defense against oxidative damage and also sustains the effects of vitamin E by regenerating the vitamin from the tocopheroxyl radical, but ubiquinol is not classified as a vitamin because it is synthesized by humans. There are varying concentrations of ubiquinol in foods, OTC products and dietary supplement products.

Dihydrocoenzyme Q10 Basic Attributes

865.381

865.36

M9NL0C577Y

2909500000

Characteristics

58.9

21.06

Solid

1.0±0.1 g/cm3

48-49ºC

866.9±65.0 °C at 760 mmHg

478.1±34.3 °C

1.526

0.2451 mg/L @ 25 °C (est)

Amber Vial, -20ºC Freezer, Under Inert Atmosphere

Safety Information

NONH for all modes of transport

Drug Information

ubiquinol

Dihydrocoenzyme Q10 Use and Manufacturing

Uses

Reduced coenzyme Q for improving nervous system cell functions

Human drugs -> Rare disease (orphan)

Computed Properties

Molecular Weight:865.4
XLogP3:20.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:31
Exact Mass:864.69956141
Monoisotopic Mass:864.69956141
Topological Polar Surface Area:58.9
Heavy Atom Count:63
Complexity:1600
Defined Bond Stereocenter Count:9
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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