Dihydrocoenzyme Q10
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Dihydrocoenzyme Q10
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CAS No:
992-78-9
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Formula:
C59H92O4
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Chemical Name:
Dihydrocoenzyme Q10
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Synonyms:
1,4-Benzenediol,2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaen-1-yl]-5,6-dimethoxy-3-methyl-;Hydroquinone,2-(3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl)-5,6-dimethoxy-3-methyl-;1,4-Benzenediol,2-(3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl)-5,6-dimethoxy-3-methyl-,(all-E)-;1,4-Benzenediol,2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl]-5,6-dimethoxy-3-methyl-;2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-Decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaen-1-yl]-5,6-dimethoxy-3-methyl-1,4-benzenediol;Coenzyme Q10,dihydro-;Coenzyme Q10-hydroquinone;Ubiquinol 50;Reduced coenzyme Q10;Dihydrocoenzyme Q10;Reduced ubiquinone Q10;Kaneka QH;Ubidecarenol;30291-37-3
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Categories:
Active Pharmaceutical Ingredients > Hormones and the Endocrine System
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CAS No:
Description
Ubiquinol (Ubiquinol-10) is a reduced form of coenzyme Q10 (CoQ10). Ubiquinol is a potent antioxidant that has the capacity to protect Vitamin E, and also helps to regenerate depleted vitamin E and Vitamin C. Ubiquinol is both lipophilic and hydrophilic and acts as transmembrane factor preventing lipid peroxidation and propagation by transferring electrons to ROS[1][2][3].
Solid
Ubiquinol-10 is a ubiquinol in which the polyprenyl substituent is decaprenyl. It has a role as a metabolite and a biomarker. It is a polyprenylhydroquinone and an ubiquinol.|Ubiquinol (CoQH2) is a reduced form of coenzyme Q10 (CoQ10) that acts as an active antioxidant that prevents the initiation and propagation of lipid peroxidation in biological membranes and human low-density lipoprotein (LDL). It plays an essential role in maintaining cellular defense against oxidative damage and also sustains the effects of vitamin E by regenerating the vitamin from the tocopheroxyl radical, but ubiquinol is not classified as a vitamin because it is synthesized by humans. There are varying concentrations of ubiquinol in foods, OTC products and dietary supplement products.
Characteristics
58.9
21.06
Solid
1.0±0.1 g/cm3
48-49ºC
866.9±65.0 °C at 760 mmHg
478.1±34.3 °C
1.526
0.2451 mg/L @ 25 °C (est)
Amber Vial, -20ºC Freezer, Under Inert Atmosphere
Dihydrocoenzyme Q10 Use and Manufacturing
Reduced coenzyme Q for improving nervous system cell functions
Human drugs -> Rare disease (orphan)
Computed Properties
Molecular Weight:865.4
XLogP3:20.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:31
Exact Mass:864.69956141
Monoisotopic Mass:864.69956141
Topological Polar Surface Area:58.9
Heavy Atom Count:63
Complexity:1600
Defined Bond Stereocenter Count:9
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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