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Devapamil

Devapamil structure

CAS No:
92302-55-1
Formula:
C26H36N2O3
Chemical Name:
Devapamil
Synonyms:
Benzeneacetonitrile,3,4-dimethoxy-α-[3-[[2-(3-methoxyphenyl)ethyl]methylamino]propyl]-α-(1-methylethyl)-;3,4-Dimethoxy-α-[3-[[2-(3-methoxyphenyl)ethyl]methylamino]propyl]-α-(1-methylethyl)benzeneacetonitrile;Devapamil;D 888;(±)-Devapamil;Desmethoxyverapamil;102268-75-7
Categories:
Organic Chemistry > Amides

Description

ChEBI: A nitrile that acts as an L-type calcium channel blocker.

Devapamil is a nitrile that acts as an L-type calcium channel blocker. It has a role as a calcium channel blocker, an anti-arrhythmia drug and a vasodilator agent. It is an aromatic ether, a nitrile and a tertiary amino compound.

Devapamil Basic Attributes

Molecular Weight：

424.585

Exact Mass：

424.58

Characteristics

PSA：

54.7

XLogP3：

4.08

Density：

1.0±0.1 g/cm3

Boiling Point：

567.0±50.0 °C at 760 mmHg

Flash Point：

296.7±30.1 °C

Refractive Index：

1.530

Drug Information

MeSH：

A class of drugs that act by selective inhibition of calcium influx through cellular membranes. (See all compounds classified as Calcium Channel Blockers.)

MeSH Entry Terms：

2-(3,4-dimethoxyphenyl)-2-isopropyl-5-((2-(3-methoxyphenyl)ethyl)(methyl)amino)pentanenitrile

Computed Properties

Molecular Weight:424.6
XLogP3:3.8
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:12
Exact Mass:424.27259301
Monoisotopic Mass:424.27259301
Topological Polar Surface Area:54.7
Heavy Atom Count:31
Complexity:560
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes