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Bevonium methyl sulfate

Bevonium methyl sulfate structure

Bevonium methyl sulfate 

structure
  • CAS No:

    5205-82-3

  • Formula:

    C22H28NO3.CH3O4S

  • Chemical Name:

    Bevonium methyl sulfate

  • Synonyms:

    Piperidinium,2-[[(2-hydroxy-2,2-diphenylacetyl)oxy]methyl]-1,1-dimethyl-,methyl sulfate (1:1);Piperidinium,2-(hydroxymethyl)-1,1-dimethyl-,methyl sulfate,benzilate;Piperidinium,2-[[(hydroxydiphenylacetyl)oxy]methyl]-1,1-dimethyl-,methyl sulfate (salt);Benzilic acid,ester with 2-(hydroxymethyl)-1,1-dimethylpiperidinium methyl sulfate;N,N-Dimethyl-2-(hydroxymethyl)piperidinium benzilate methyl sulfate;Acabel;Bevonium methyl sulfate;Piribenzil methyl sulfate;Piribenzil methosulfate;CG 201;Bevonium metilsulfate;2-((2-Hydroxy-2,2-diphenylacetoxy)methyl)-1,1-dimethylpiperidin-1-ium methyl sulfate;2-([[Hydroxy(diphenyl)acetyl]oxy]methyl)-N,N-dimethylpiperidinium methyl sulfate;23277-37-4

Description

Crystalline Solid


Bevonium methyl sulfate is a glycolate ester, a member of piperidines and an azaheterocycle sulfate salt.

Bevonium methyl sulfate Basic Attributes

465.55974

465.182

226-001-8

DTXSID3046615

Characteristics

121

3.22720

134.5 °C

Hygroscopic, -20°C Freezer, Under Inert Atmosphere

Oral-rat LD50: 5080 mg/kg; Oral-Mouse LD50: 1360 mg/kg

Thermal decomposition emits toxic nitrogen oxides and sulfur oxide fumes

Safety Information

The warehouse is low-temperature, ventilated and dry

P264, P270, P301+P312, P330, P501

H302

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P301+P312, P330, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory.

Toxicity

moderately toxic

Drug Information

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)

2-(hydroxymethyl)-N,N-dimethylpiperidinium benzilate

Bevonium methyl sulfate Use and Manufacturing

Used as an anticholinergic, antispasmodic, and brochodilator. Antibacterial.

Computed Properties

Molecular Weight:465.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:6
Exact Mass:465.18212350
Monoisotopic Mass:465.18212350
Topological Polar Surface Area:121
Heavy Atom Count:32
Complexity:537
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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