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Home > Encyclopedia > TENUAZONIC ACID COPPER FROM ALTERNARIA A

TENUAZONIC ACID COPPER FROM ALTERNARIA A

TENUAZONIC ACID COPPER FROM ALTERNARIA A structure

TENUAZONIC ACID COPPER FROM ALTERNARIA A 

structure
  • CAS No:

    610-88-8

  • Formula:

    C10H15NO3

  • Chemical Name:

    TENUAZONIC ACID COPPER FROM ALTERNARIA A

  • Synonyms:

    (S)-3-Acetyl-5-(S)-sec-butyltetramic acid;(S)-3-Acetyl-5-sec-butyl-4-hydroxy-3-pyrrolin-2-one;2h-pyrrol-2-one,3-acetyl-1,5-dihydro-4-hydroxy-5-(1-methylpropyl)-,(s-(r*,r;l-3-pyrrolin-2-on;tenuazonicacid;TENUAZONIC ACID COPPER FROM ALTERNARIA A;tenuazonic acid copper from alternaria*alternata;TenuazonicacidfromAlternariasp

  • Categories:

    Analytical Chemistry  >  Standard

Description

Tenuazonic acid, belonging to tetramic acids that are the largest family of natural products, is a putative nonhost-selective mycotoxin isolated from Alternaria alternate[1]. Tenuazonic acid blocks electron transport beyond primary quinone acceptor (QA) by interacting with D1 protein and it is a broad-spectrum and effective photosystem II (PSII) inhibitor[2].


Solid


3-Acetyl-5-sec-butyl-4-hydroxy-3-pyrrolin-2-one. A metabolite found in a strain of the fungus Alternaria tenuis Auct. which functions as an antibiotic with antiviral and antineoplastic properties, and may also act as a mycotoxin.

TENUAZONIC ACID COPPER FROM ALTERNARIA A Basic Attributes

197.23

197.23

3589518

Light yellow to brown

29337900

Characteristics

66.40000

0.81

Solid

1.1575 (rough estimate)

74.5°C

bp0.035 117°

196.4±28.7 °C

1.5480 (estimate)

2-8°C

20D -128° (c = 1.0 in methanol); -132 ± 2° (c = 0.5 in CHCl3)

4.50±1.00(Predicted)

2-8°C

Safety Information

III

6.1(b)

UN 2811 6.1/PG 3

3

Xn

UY7425000

Xn

P301 + P310

22

UN 2811 6.1/PG 3

|Danger|H301 (97.44%): Toxic if swallowed [Danger Acute toxicity, oral]|P264, P270, P301+P310, P321, P330, P405, and P501|Aggregated GHS information provided by 39 companies from 2 notifications to the ECHA C&L Inventory.

Drug Information

Chemical substances, produced by microorganisms, inhibiting or preventing the proliferation of neoplasms. (See all compounds classified as Antibiotics, Antineoplastic.)|Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly. (See all compounds classified as Antiviral Agents.)

Acid, Tenuazonic

TENUAZONIC ACID COPPER FROM ALTERNARIA A Use and Manufacturing

An alternaria mycotoxin, found in common edible crops.It inhibits protein synthesis in fibroblasts.


Tenuazonic acid is potent tetramic acid mycotoxin produced by several fungal genera, notably Alternaria. Tenuazonic acid exhibits antitumour, antiviral and antibacterial activity.

Computed Properties

Molecular Weight:197.23
XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:197.10519334
Monoisotopic Mass:197.10519334
Topological Polar Surface Area:66.4
Heavy Atom Count:14
Complexity:307
Undefined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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