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Home > Encyclopedia > 1-(3,4-dichlorophenyl)-5-isopropylbiguanide monohydrochloride

1-(3,4-dichlorophenyl)-5-isopropylbiguanide monohydrochloride

1-(3,4-dichlorophenyl)-5-isopropylbiguanide monohydrochloride structure

1-(3,4-dichlorophenyl)-5-isopropylbiguanide monohydrochloride 

structure
  • CAS No:

    6001-93-0

  • Formula:

    C11H16Cl3N5

  • Chemical Name:

    1-(3,4-dichlorophenyl)-5-isopropylbiguanide monohydrochloride

  • Synonyms:

    1-(3,4-dichlorophenyl)-5-isopropylbiguanide monohydrochloride;1-(3,4-Dichlorophenyl)-5-isopropylbiguanide hydrochloride;Chloroproguanide hydrochloride;Proguanil Related CoMpound F;Proguanil USP Related Compound F;Proguanil USP RC F;Proguanil Impurity 6(Proguanil USP RC F);Proguanil Related Compound F (1-(3,4-dichlorophenyl)-5-isopropylbiguanide hydrochloride) (1568084)

  • Categories:

    Analytical Chemistry  >  Standard

1-(3,4-dichlorophenyl)-5-isopropylbiguanide monohydrochloride Basic Attributes

324.63724

323.047

227-846-5

6T04V14CU9

2925294500

Characteristics

88.8

4.71870

246-247 °C

LD50 oral in mouse: 100mg/kg

Safety Information

UN 2811 6.1 / PGIII

1

DU1788900

UN 2811 6.1 / PGIII

Drug Information

Agents used in the treatment of malaria. They are usually classified on the basis of their action against plasmodia at different stages in their life cycle in the human. (From AMA, Drug Evaluations Annual, 1992, p1585) (See all compounds classified as Antimalarials.)

chlorproguanil

1-(3,4-dichlorophenyl)-5-isopropylbiguanide monohydrochloride Use and Manufacturing

Uses

Proguanil Related Compound F USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monograph such as Proguanil Hydrochloride

Human drugs -> Rare disease (orphan)

Computed Properties

Molecular Weight:324.6
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:323.047129
Monoisotopic Mass:323.047129
Topological Polar Surface Area:88.8
Heavy Atom Count:19
Complexity:329
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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