Dihydrocortisol
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Dihydrocortisol
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CAS No:
1482-50-4
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Formula:
C21H32O5
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Chemical Name:
Dihydrocortisol
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Synonyms:
Pregnane-3,20-dione,11,17,21-trihydroxy-,(5β,11β)-;5β-Pregnane-3,20-dione,11β,17,21-trihydroxy-;(5β,11β)-11,17,21-Trihydroxypregnane-3,20-dione;11β,17α,21-Trihydroxy-5β-pregnane-3,20-dione;Cortisol,dihydro-;Dihydrocortisol;5β-Dihydrocortisol;11β,17,21-Trihydroxy-5β-pregnane-3,20-dione;NSC 15473
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CAS No:
Description
Solid
5beta-dihydrocortisol is a 17alpha-hydroxy-C21-steroid that is cortisol in which the 4-5 double bond has undergone formal hydrogenation to give the corresponding 5beta- steroid. It is a 21-hydroxy steroid, a 17alpha-hydroxy-C21-steroid, an 11beta-hydroxy steroid, a 3-oxo-5beta-steroid, a primary alpha-hydroxy ketone, a triol, a secondary alcohol, a diketone, a 20-oxo steroid and a tertiary alpha-hydroxy ketone.
Dihydrocortisol Use and Manufacturing
5β-Dihydrocortisol, is a derivative of Cortisol (H714615), which is a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland.
Lipids -> Sterol Lipids [ST] -> Steroids [ST02] -> C21 steroids (gluco/mineralocorticoids, progestogins) and derivatives [ST0203]
Computed Properties
Molecular Weight:364.5
XLogP3:2.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:364.22497412
Monoisotopic Mass:364.22497412
Topological Polar Surface Area:94.8
Heavy Atom Count:26
Complexity:632
Defined Atom Stereocenter Count:8
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes