N-Benzyl-p-toluenesulfonamide
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N-Benzyl-p-toluenesulfonamide
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CAS No:
1576-37-0
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Formula:
C14H15NO2S
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Chemical Name:
N-Benzyl-p-toluenesulfonamide
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Synonyms:
Benzenesulfonamide,4-methyl-N-(phenylmethyl)-;p-Toluenesulfonamide,N-benzyl-;4-Methyl-N-(phenylmethyl)benzenesulfonamide;N-Benzyl-p-toluenesulfonamide;N-Tosylbenzylamine;N-Benzyl-p-tosylamide;N-Benzyl-4-methylbenzenesulfonamide;NSC 37123;Benzyl(4-toluenesulfonyl)amine
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CAS No:
Characteristics
54.6
2.7
1.204±0.06 g/cm3(Predicted)
113 °C
419.1±48.0 °C(Predicted)
207.3ºC
1.589
25.9 [ug/mL]
Safety Information
XT5490000
P264, P270, P301+P310, P321, P330, P405, P501
H301
|Danger|H301 (95%): Toxic if swallowed [Danger Acute toxicity, oral]|P264, P270, P301+P310, P321, P330, P405, and P501|Aggregated GHS information provided by 40 companies from 3 notifications to the ECHA C&L Inventory.
N-Benzyl-p-toluenesulfonamide Use and Manufacturing
A potent inhibitor of skeletal muscle Ca2+-stimulated myosin S1 ATPase (IC50 approx. 5uM) activity. Reversible blocks the gliding motility. Also weakens myosin interaction with F-actin. Does not affect platelet myosin II A potent inhibitor of skeletal muscle Ca2+-stimulated myosin S1 ATPase (IC50 approx. 5uM) activity. Reversible blocks the gliding motility. Also weakens myosin’s interaction with F-actin. Does not affect platelet myosin II.Selective inhibitor of the ATPase activity
Computed Properties
Molecular Weight:261.34
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:261.08234989
Monoisotopic Mass:261.08234989
Topological Polar Surface Area:54.6
Heavy Atom Count:18
Complexity:333
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
