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Irisolidone

Irisolidone structure

Irisolidone 

structure
  • CAS No:

    2345-17-7

  • Formula:

    C17H14O6

  • Chemical Name:

    Irisolidone

  • Synonyms:

    4H-1-Benzopyran-4-one,5,7-dihydroxy-6-methoxy-3-(4-methoxyphenyl)-;Isoflavone,5,7-dihydroxy-4′,6-dimethoxy-;5,7-Dihydroxy-6-methoxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one;Irisolidone;4′-Methoxytectorigenin;4′-O-Methyltectorigenin

Description

Irisolidone is a major isoflavone found in Pueraria lobata flowers. Irisolidone exhibits potent hepatoprotective activity. Irisolidone shows the high efficacy for volume-regulated anion channels (VRAC) blockade[1][2][3].


Irisolidone is a member of 4'-methoxyisoflavones.

Irisolidone Basic Attributes

314.293

314.29

081ORX70ZR

2914509090

Characteristics

85.2

2.88840

1.402g/cm3

190-191 °C

565.5ºC at 760mmHg

212.3ºC

1.645

H2O: Practically insoluble (0.05 g/L) (25 ºC)

Drug Information

5,7-dihydroxy-6-methoxy-3-(4-methoxyphenyl)-4H-chromen-4-one

Irisolidone Use and Manufacturing

Polyketides [PK] -> Flavonoids [PK12] -> Isoflavonoids [PK1205]

Computed Properties

Molecular Weight:314.29
XLogP3:3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:314.07903816
Monoisotopic Mass:314.07903816
Topological Polar Surface Area:85.2
Heavy Atom Count:23
Complexity:468
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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