Carphenazine
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Carphenazine
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CAS No:
2622-30-2
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Formula:
C24H31N3O2S
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Chemical Name:
Carphenazine
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Synonyms:
1-Propanone,1-[10-[3-[4-(2-hydroxyethyl)-1-piperazinyl]propyl]-10H-phenothiazin-2-yl]-;1-Propanone,1-[10-[3-[4-(2-hydroxyethyl)-1-piperazinyl]propyl]phenothiazin-2-yl]-;1-[10-[3-[4-(2-Hydroxyethyl)-1-piperazinyl]propyl]-10H-phenothiazin-2-yl]-1-propanone;Carphenazine;Proketazine;Carphenazin;Carfenazine
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CAS No:
Description
Carphenazine is an antipsychotic drug, used in hospitalized patients in the management of chronic schizophrenic psychoses.
Drug Information
Used in the treatment of acute or chronic schizophrenic reactions in hospitalized patients.
Carphenazine is a phenothiazine antipsychotic agent with a piperazine side-chain.
A yellow, powdered, phenothiazine antipsychotic agent used in the treatment of acute or chronic schizophrenia. The term "phenothiazines" is used to describe the largest of the five main classes of neuroleptic antipsychotic drugs. These drugs have antipsychotic and, often, antiemetic properties, although they may also cause severe side effects such as akathisia, tardive dyskinesia and extrapyramidal symptoms. Carphenazine blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; depresses the release of hypothalamic and hypophyseal hormones and is believed to depress the reticular activating system thus affecting basal metabolism, body temperature, wakefulness, vasomotor tone, and emesis.
Carphenazine Use and Manufacturing
Antipsychotic.
Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients
Computed Properties
Molecular Weight:425.6
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:8
Exact Mass:425.21369841
Monoisotopic Mass:425.21369841
Topological Polar Surface Area:72.3
Heavy Atom Count:30
Complexity:555
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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