Ergovaline
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Ergovaline
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CAS No:
2873-38-3
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Formula:
C29H35N5O5
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Chemical Name:
Ergovaline
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Synonyms:
Ergotaman-3′,6′,18-trione,12′-hydroxy-2′-methyl-5′-(1-methylethyl)-,(5′α)-;Ergovaline;8H-Oxazolo[3,2-a]pyrrolo[2,1-c]pyrazine,ergotaman-3′,6′,18-trione deriv.;Indolo[4,3-fg]quinoline,ergotaman-3′,6′,18-trione deriv.;(5′α)-12′-Hydroxy-2′-methyl-5′-(1-methylethyl)ergotaman-3′,6′,18-trione;Indolo[4,3-fg]quinoline-9-carboxamide,4,6,6a,7,8,9-hexahydro-7-methyl-N-(octahydro-10b-hydroxy-5-isopropyl-2-methyl-3,6-dioxo-8H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-;33066-64-7
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CAS No:
Drug Information
Drugs used to cause constriction of the blood vessels. (See all compounds classified as Vasoconstrictor Agents.)
12'-hydroxy-2'-methyl-5' alpha-(1-methylethyl)-ergotaman-3',6',18-trione
Ergovaline Use and Manufacturing
Ergovaline is an ergopetine alkaloid commonly found in endophyte-infected species of tall grass fescue. Ergovaline is known to cause tall fescue toxicosis and is toxic to cattle feeding on the infected grass as it inhibits vesicular glutamate transporter activity in cow cerebral synatic vesicles.
Computed Properties
Molecular Weight:533.6
XLogP3:1.4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:533.26381923
Monoisotopic Mass:533.26381923
Topological Polar Surface Area:118
Heavy Atom Count:39
Complexity:1130
Defined Atom Stereocenter Count:6
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes