1-Methyl-L-histidine
-
1-Methyl-L-histidine
structure -
-
CAS No:
332-80-9
-
Formula:
C7H11N3O2
-
Chemical Name:
1-Methyl-L-histidine
-
Synonyms:
L-Histidine,1-methyl-;Histidine,1-methyl-,L-;1-Methyl-L-histidine;1-Methylhistidine;1-N-Methyl-L-histidine;N1-Methyl-L-histidine;NSC 524367;(S)-2-Amino-3-(1-methyl-1H-imidazol-4-yl)propanoic acid;τ-Methylhistidine;π-N-Methyl-L-histidine;(2S)-2-Amino-3-(1-methyl-1H-imidazol-4-yl)propanoic acid
- Categories:
-
CAS No:
Description
1-Methyl-L-histidine is an objective indicator of meat ingestion and exogenous 3-methylhistidine (3MH) intake.
Solid
N(tele)-methyl-L-histidine is a L-histidine derivative in which the methyl group is at N(tele)-position. It has a role as a human metabolite. It is a L-histidine derivative and a non-proteinogenic L-alpha-amino acid.|1-Methylhistidine is a histidine derivative that has a methyl group bound to the nitrogen at position 1 and results from the metabolism of the dipeptide anserine. Urinary levels of 1-methylhistidine may be indicative of myofibrillar protein degradation or a high protein diet.
1-Methyl-L-histidine Basic Attributes
169.18
169.18
206-368-0
583O01BJ32
DTXSID50186848
C118886
2933290090
Characteristics
81.1
-1.31
Solid
1.4±0.1 g/cm3
269-270 °C
415.0±35.0 °C at 760 mmHg
204.8±25.9 °C
1.613
200 g/kg
-24 º (c=2% in H2O)
133.1 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|139.64 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|129 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine]|133.4 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|138.4 Ų [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|133.6 Ų [M+H]+
1-Methyl-L-histidine Use and Manufacturing
The urinary 1- and 3-methylhistidine (1- and 3-MH) metabolites as potential biomarkers of skeletal muscle toxicity. These metabolites were highly correlated to sex-, dose-, and time-dependent development of cerivastatin-induced myotoxicity. Natural but non-proteinogenic amino acid; employed as index of muscle protein breakdown.
Computed Properties
Molecular Weight:169.18
XLogP3:-3.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:169.085126602
Monoisotopic Mass:169.085126602
Topological Polar Surface Area:81.1
Heavy Atom Count:12
Complexity:174
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of 1-Methyl-L-histidine
-
![China]()
CN
5 YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives -
![China]()
CN
5 YRS
Business licensedTrader Supplier of PVC resin,pvc paste resin,melamineInquiryCAS No.: 332-80-9Grade: Industrial GradeContent: 99%
Learn More Other Chemicals
-
1-Methyl-L-histidine hydrochloride (1:1)
200926-96-1
-
L-Cysteine
52-90-4
-
1-chloro-6-Methyl-5-nitroisoquinoline
943606-84-6
-
2-chloro-N-(2-oxothiolan-3-yl)acetamide Formula
84611-22-3
-
N-[(Phenylmethoxy)carbonyl]-L-phenylalanylglycine Formula
13122-99-1
-
(αR)-α-[(Methoxycarbonyl)amino]benzeneacetic acid Formula
50890-96-5
-
3,4,5-Trimethoxy-N-(2-methoxyethyl)-N-(4-phenyl-2-thiazolyl)-benzamide Structure
461000-66-8
-
5-(4-Hydroxyphenyl)-2,4-imidazolidinedione Structure
2420-17-9
-
What is γ-Aminobenzenepropanol
14593-04-5
-
What is tert-Butyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate
170491-63-1