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Hydracarbazine

Hydracarbazine structure

Hydracarbazine 

structure
  • CAS No:

    3614-47-9

  • Formula:

    C5H7N5O

  • Chemical Name:

    Hydracarbazine

  • Synonyms:

    3-Pyridazinecarboxamide,6-hydrazinyl-;3-Pyridazinecarboxamide,6-hydrazino-;6-Hydrazinyl-3-pyridazinecarboxamide;Hydracarbazine;Hydracarbizine;3-Hydrazino-6-carbamoylpyridazine;6-Hydrazino-3-pyridazinecarboxamide;Hydracarbazin;TH 1325

Description

Hydracarbazine is a heteroarene and an aromatic amide.|Hydracarbazine is a pyridazine that has found use as an antihypertensive agent It was once marketed in France under the tradename Normatensyl.|Hydracarbazine is a hydrazinopyridazine-based diuretic with antihypertensive activity. Hydracarbazine is no longer marketed.

Hydracarbazine Basic Attributes

153.145

153.14

222-788-7

6CTK2FB9QM

DTXSID30189716

C74255

2933990090

Characteristics

107

-1.4

1.513g/cm3

249-250 °C (decomp)

549.1ºC at 760mmHg

285.9ºC

1.717

Drug Information

Was used for the treatment of hypertension.

Relaxes vascular smooth muscle.

Likely acts similarly to hydralazine, a related compound, which interferes with calcium release from the sarcoplasmic reticulum in response to inositol.

Computed Properties

Molecular Weight:153.14
XLogP3:-1.4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:153.06505986
Monoisotopic Mass:153.06505986
Topological Polar Surface Area:107
Heavy Atom Count:11
Complexity:150
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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