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Isopropamide iodide

Isopropamide iodide structure

CAS No:
71-81-8
Formula:
C23H33N2O.I
Chemical Name:
Isopropamide iodide
Synonyms:
Benzenepropanaminium,γ-(aminocarbonyl)-N-methyl-N,N-bis(1-methylethyl)-γ-phenyl-,iodide (1:1);(3-Carbamoyl-3,3-diphenylpropyl)diisopropylmethylammonium iodide;Ammonium,(3-carbamoyl-3,3-diphenylpropyl)diisopropylmethyl-,iodide;Benzenepropanaminium,γ-(aminocarbonyl)-N-methyl-N,N-bis(1-methylethyl)-γ-phenyl-,iodide;R 79;SKF 4740;Darbid;2,2-Diphenyl-4-diisopropylaminobutyramide methiodide;Isopropamide iodide;Priamide;Dipramid;Dipramide;Sanulcin;Tyrimide;Isamid;Marygin-M;5579 MD;Piaccamide;Priazimide;Isoproponum iodide;137405-07-3;2090-55-3;3374-86-5
Categories:
Analytical Chemistry > Standard

Description

Isopropamide iodide is a long-acting quaternary anticholinergic agent. Isopropamide iodide is used in peptic ulcer and other gastrointestinal disorders marked by hyperacidity and hypermotility[1][2].

Isopropamide iodide is a diarylmethane.

Isopropamide iodide Basic Attributes

Molecular Weight：

480.43

Exact Mass：

480.16400

EC Number：

200-766-8

UNII：

E0KNA372SZ

NSC Number：

757066

DSSTox ID：

DTXSID30221221

HScode：

2924299090

Characteristics

PSA：

43.09000

XLogP3：

1.81580

Density：

1.2711 (estimate)

Melting Point：

199 °C (decomp)

Toxicity：

LD50 oral in rat: > 10gm/kg

Collision Cross Section：

186.9 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

36/37/38

safety instructions：

26-36

RTECS Number：

BP0693200

Marks：

Precautionary statement(s)：

P305 + P351 + P338

Hazard Statements：

H315-H319-H335

GHS Classification：

|Warning|H315 (98%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 50 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH Entry Terms：

Bispan

Isopropamide iodide Use and Manufacturing

Uses

anticholinergic

Use Classification：

Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients

Computed Properties

Molecular Weight:480.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:8
Exact Mass:480.16376
Monoisotopic Mass:480.16376
Topological Polar Surface Area:43.1
Heavy Atom Count:27
Complexity:419
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes