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Home > Encyclopedia > N-Cyclohexyl-4-toluenesulfonamide

N-Cyclohexyl-4-toluenesulfonamide

N-Cyclohexyl-4-toluenesulfonamide structure

N-Cyclohexyl-4-toluenesulfonamide 

structure
  • CAS No:

    80-30-8

  • Formula:

    C13H19NO2S

  • Chemical Name:

    N-Cyclohexyl-4-toluenesulfonamide

  • Synonyms:

    Benzenesulfonamide,N-cyclohexyl-4-methyl-;p-Toluenesulfonamide,N-cyclohexyl-;N-Cyclohexyl-4-methylbenzenesulfonamide;N-Cyclohexyl-p-toluenesulfonamide;Santicizer 1H;N-Cyclohexyl-4-toluenesulfonamide;(Tosylamino)cyclohexane;N-Cyclohexyl-4-methylphenylsulfonamide;NSC 14856;NSC 48143;Topcizer 8

Description

white or yellowish solid


Yellowish-brown fused mass or white crystalline solid. Little or no odor. (NTP, 1992)


Yellowish-brown fused mass or white crystalline solid. Little or no odor. (NTP, 1992)

N-Cyclohexyl-4-toluenesulfonamide Basic Attributes

253.361

253.36

201-268-3

0QPV1AE9EM

48143|14856

DTXSID1024885

2935009090

Characteristics

54.55000

3.49

Yellowish-brown fused mass or white crystalline solid. Little or no odor. (NTP, 1992)

1.2±0.1 g/cm3

86.5-88.0 °C

386.3±35.0 °C at 760 mmHg

187.4±25.9 °C

1.564

<0.1 g/100 mL at 21 ºC

less than 1 mm Hg at 68° F (NTP, 1992)

Insoluble in water.

Amines, Phosphines, and Pyridines

Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).

Safety Information

S22-S24/25

XT5617000

Stable. Incompatible with strong oxidizing agents.

P264, P280, P305+P351+P338, P33, P313

H319

Flash point data for this compound is not available; however, it is probably combustible. (NTP, 1992)

|Warning|H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]|P264, P280, P305+P351+P338, and P337+P313|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory.

Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. A water spray may also be used. (NTP, 1992)

SMALL SPILLS AND LEAKAGE: Should a spill occur while you are handling this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with 60-70% ethanol and transfer the dampened material to a suitable container. Use absorbent paper dampened with 60-70% ethanol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. STORAGE PRECAUTIONS: You should store this material in a refrigerator. (NTP, 1992)

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter). (NTP, 1992)

Drug Information

SYMPTOMS: Symptoms of exposure to this compound may include skin and eye irritation. ACUTE/CHRONIC HAZARDS: When heated to decomposition this compound may emit toxic fumes of carbon monoxide, oxides of nitrogen, oxides of sulfur and ammonia. (NTP, 1992)

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Generally, the induction of vomiting is NOT recommended outside of a physician's care due to the risk of aspirating the chemical into the victim's lungs. However, if the victim is conscious and not convulsing and if medical help is not readily available, consider the risk of inducing vomiting because of the high toxicity of the chemical ingested. Ipecac syrup or salt water may be used in such an emergency. IMMEDIATELY transport the victim to a hospital. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

N-Cyclohexyl-4-toluenesulfonamide Use and Manufacturing

Benzenesulfonamide, N-cyclohexyl-4-methyl-: INACTIVE

Computed Properties

Molecular Weight:253.36
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:253.11365002
Monoisotopic Mass:253.11365002
Topological Polar Surface Area:54.6
Heavy Atom Count:17
Complexity:320
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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