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Colchicoside

Colchicoside structure

Colchicoside 

structure
  • CAS No:

    477-29-2

  • Formula:

    C27H33NO11

  • Chemical Name:

    Colchicoside

  • Synonyms:

    Acetamide,N-[(7S)-3-(β-D-glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl]-;Colchicoside;Acetamide,N-[3-(β-D-glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl]-,(S)-;Benzo[a]heptalene,acetamide deriv.;N-[(7S)-3-(β-D-Glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide;3-Demethylcolchicine glucoside;1329-53-9;1355-69-7

  • Categories:

    Biochemical Engineering  >  Chinese Herbs

Description

Pale Yellow Solid


Colchicoside is a carbotricyclic compound, an alkaloid and a member of acetamides.

Colchicoside Basic Attributes

547.554

547.55

207-513-0

DYD0I854K7

Characteristics

173.24000

-1.76

1.4±0.1 g/cm3

194-197°C

929.0±65.0 °C at 760 mmHg

515.6±34.3 °C

1.636

Refrigerator

0mmHg at 25°C

Oral-mouse LD50: 84 mg/kg; peritoneal-mouse LD50: 280 mg/kg

Combustible; Fire breaks down toxic nitrogen oxide fumes

Safety Information

Treasury is low temperature, ventilated, dry; stored separately from food raw materials

Toxicity

highly toxic

Drug Information

colchicoside

Colchicoside Use and Manufacturing

A significantly toxic Colchicine analog with no anti-inflammatory properties.

Computed Properties

Molecular Weight:547.5
XLogP3:-1.1
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:7
Exact Mass:547.20536087
Monoisotopic Mass:547.20536087
Topological Polar Surface Area:173
Heavy Atom Count:39
Complexity:1010
Defined Atom Stereocenter Count:6
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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