d-Borneol
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d-Borneol
structure -
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CAS No:
464-43-7
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Formula:
C10H18O
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Chemical Name:
d-Borneol
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Synonyms:
Bicyclo[2.2.1]heptan-2-ol,1,7,7-trimethyl-,(1R,2S,4R)-;Borneol,(1R,2S,4R)-(+)-;Bicyclo[2.2.1]heptan-2-ol,1,7,7-trimethyl-,(1R-endo)-;(1R,2S,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol;d-Borneol;(+)-(2S)-Borneol;Borneol,(+)-;(+)-Borneol;(+)-endo-Borneol;(1R)-(+)-Borneol;d-(+)-Borneol;(1R)-endo-Borneol;(+)-2-Borneol
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CAS No:
Description
(+)-Borneol (d-Borneol) is a natural bicyclic monoterpene used for analgesia and anesthesia in traditional Chinese medicine; enhances GABA receptor activity with an EC50 of 248 μM.
Characteristics
20.2
2.69
Borneol appears as a white colored lump-solid with a sharp camphor-like odor. Burns readily. Slightly denser than water and insoluble in water. Used to make perfumes.
1.0±0.1 g/cm3
208 °C
212 deg C
150 °F
1.502
soluble in alcohol and ether
2-8°C
5.02X10-2 mm Hg at 25 deg C
36 º (C=5 IN ETOH)
Piney, camphor-like odor
Burning taste somewhat reminiscent of mint
Safety Information
III
4.1
UN 1312 4.1/PG 3
3
11-20/21/22
16-33-36-7/9
ED7060000
F,Xn
Stable under recommended storage conditions.
P210
H228
d-Borneol Use and Manufacturing
Borneol, the main components of borneol and isoborneol, have anti-anoxia effects; borneol and isoborneol have a sedative effect; local application of borneol has a slight irritation to sensory nerves, has a certain pain relief and mild antiseptic effect; The mesenteric is absorbed rapidly, it can pass through the blood-brain barrier within 5 minutes of administration, and it accumulates in the brain for a long time and the amount is quite high. This provides a preliminary experimental basis for the aromatic resuscitation effect of borneol; higher concentration (0.5%) Staphylococcus, streptococcus, pneumococcus, Escherichia coli and some pathogenic dermatophytes, etc. have inhibitory effects; it can induce labor in middle and late pregnancy mice.
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