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2′,3′,5′-Tri-O-acetyluridine

2′,3′,5′-Tri-O-acetyluridine structure

CAS No:
4105-38-8
Formula:
C15H18N2O9
Chemical Name:
2′,3′,5′-Tri-O-acetyluridine
Synonyms:
Uridine,2′,3′,5′-triacetate;2′,3′,5′-Tri-O-acetyluridine;2′,3′,5′-Triacetyluridine;Tri-O-acetyl uridine;Uridine triacetate;PN 401;RG 2133;Vistonuridine;Xuriden;Triacetyluridine;Vistogard;Chembridge 5106522;293738-13-3;1606159-79-8
Categories:
Biochemical Engineering > Nucleoside Drugs

Description

Uridine triacetate (Tri-O-acetyl uridine) is an orally active prodrug of Uridine. Uridine triacetate (Tri-O-acetyl uridine) is lipophilic, is quickly absorbed in the gut, and is rapidly deacetylated in the circulation to yield free uridine. Uridine triacetate (Tri-O-acetyl uridine) is uesd for the prevention and treatment of life-threatening 5-fluorouracil and capecitabine toxicity. Uridine triacetate (Tri-O-acetyl uridine) delivers high concentrations of uridine, which competes with tox

2′,3′,5′-Tri-O-acetyluridine Basic Attributes

Molecular Weight：

370.31

Exact Mass：

370.31

EC Number：

223-881-5

HScode：

29349990

Characteristics

PSA：

138

XLogP3：

-1.13950

Appearance：

white or almost white crystalline powder

Density：

1.4±0.1 g/cm3

Melting Point：

130-132 °C

Refractive Index：

1.552

Storage Conditions：

−20°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

safety instructions：

24/25

Computed Properties

Molecular Weight:370.31
XLogP3:-0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:8
Exact Mass:370.10123016
Monoisotopic Mass:370.10123016
Topological Polar Surface Area:138
Heavy Atom Count:26
Complexity:660
Defined Atom Stereocenter Count:4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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Guide of 2′,3′,5′-Tri-O-acetyluridine

Description
Basic Attributes
Characteristics
Safety Information
Computed Properties
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2′,3′,5′-Tri-O-acetyluridine

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