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Home > Encyclopedia > 4-Oxo-4H-1-benzopyran-2-carboxylic acid

4-Oxo-4H-1-benzopyran-2-carboxylic acid

4-Oxo-4H-1-benzopyran-2-carboxylic acid structure

4-Oxo-4H-1-benzopyran-2-carboxylic acid 

structure
  • CAS No:

    4940-39-0

  • Formula:

    C10H6O4

  • Chemical Name:

    4-Oxo-4H-1-benzopyran-2-carboxylic acid

  • Synonyms:

    4H-1-Benzopyran-2-carboxylic acid,4-oxo-;4-Oxo-4H-1-benzopyran-2-carboxylic acid;2-Chromonecarboxylic acid;Chromocarb;4-Oxochromene-2-carboxylic acid;Atremon;LP 1;4-Oxo-4H-benzopyran-2-carboxylic acid;4-Oxo-4H-chromene-2-carboxylic acid;Campel;918124-20-6

  • Categories:

    Pharmaceutical Intermediates  >  Heterocyclic Compound

Description

Chromocarb is a synthetic vasoprotectant.


4-oxo-1-benzopyran-2-carboxylic acid is a member of chromones.

4-Oxo-4H-1-benzopyran-2-carboxylic acid Basic Attributes

190.15

190.15

146442

225-583-0

FY38S0790W

758218

DTXSID6045878

2918300090

Characteristics

63.6

1.6

White to beige Powder

1.5±0.1 g/cm3

260 °C (decomp)

337°C at 760 mmHg

138.9±21.4 °C

1.640

Sparingly soluble with water.alcohol: soluble

LD50 intraperitoneal in mouse: 585mg/kg

134 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Safety Information

3

36/37/38

26-36-37/39

DJ2476000

Xi

Irritant

P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501

H315

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 44 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

4-oxo-4H-1-benzopyran-2-carboxylic acid

4-Oxo-4H-1-benzopyran-2-carboxylic acid Use and Manufacturing

4-oxo-4H-1-Benzopyran-2-carboxylic Acid acts as an inhibitor of monoamine oxidase A & B. Also functions as a novel type of tyrosine phosphatase 1B inhibitor in studies, due to a structure derived from formylchromone.

Computed Properties

Molecular Weight:190.15
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:190.02660867
Monoisotopic Mass:190.02660867
Topological Polar Surface Area:63.6
Heavy Atom Count:14
Complexity:305
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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