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Cholesterol

Cholesterol structure

CAS No:
57-88-5
Formula:
C27H46O
Chemical Name:
Cholesterol
Synonyms:
Cholest-5-en-3-ol (3β)-;Cholesterol;(3β)-Cholest-5-en-3-ol;Cholest-5-en-3β-ol;Cholesterin;5:6-Cholesten-3β-ol;Dythol;3β-Hydroxycholest-5-ene;Provitamin D;Cholesteryl alcohol;(-)-Cholesterol;Δ5-Cholesten-3β-ol;Lidinit;Lidinite;NSC 8798;SyntheChol;Marine Cholesterol;80356-14-5;80356-33-8;209124-38-9;218965-24-3;262418-13-3;378185-03-6;676322-57-9;732297-95-9;793670-51-6;849593-11-9;856708-55-9;2016865-06-6;2363129-31-9
Categories:
Cosmetic Ingredient > Light Stabilizer

Description

Cholesterol is the major sterol in mammals, and its importance in fundamental cellular processes is becoming more appreciated. IC50 value:Target:In vitro: GT1-7 hypothalamic cells subjected to cholesterol depletion in vitro produced 20-31% reductions in cellular cholesterol content, similar to the decrease in cholesterol synthesis observed in diabetes [1].In vivo:

Vat Yellow 1 is sort of vat dye. Molecular structure of Vat Yellow 1 is anthraquinone.

Cholesterol Basic Attributes

Molecular Weight：

386.65400

Exact Mass：

386.65

EC Number：

200-353-2

HScode：

2906131000

Characteristics

PSA：

20.23000

XLogP3：

7.38870

Appearance：

Solid

Density：

1.067 g/cm³ @ Temp: 20 °C

Melting Point：

148.5 °C

Boiling Point：

360 °C

Flash Point：

250ºC

Refractive Index：

1.525

Water Solubility：

H2O: negligible soluble

Storage Conditions：

2-8ºC

Specific rotation：

Specific rotation: -34 to 38 deg @ 25 °C

Odor：

Almost odorless

Safety Information

Transport codes：

UN 1170 3/PG 3

wgk germany：

hazard class code：

R10

safety instructions：

S22-S24/25

RTECS Number：

FZ8400000

Marks：

Stability/Shelf Life：

Stable under normal shipping and handling conditions.

Precautionary statement(s)：

P201-P261-P304 + P340 + P312-P305 + P351 + P338-P308 + P313-P403 + P233

Hazard Statements：

H302-H315-H319-H331-H336-H351-H361d-H372

RIDADR：

UN 1170 3/PG 3

Cholesterol Use and Manufacturing

Uses

1. Analeptic, antibacterial
2. Cholesterol is a major component of all biological membranes; ~25% of total brain lipid is Cholesterol. Cholesterol is the principal sterol of the higher animals. Cholesterol was found in all body tissues, especial in the brain, spinal cord, and in animal fats or oils. Cholesterol is the main constituent of gallstones.
3. Cholesterol be used as pharmaceutical intermediates and be used as synthetic materials of liquid crystal polymers.

Manufacturing Info：

Cholest-5-en-3-ol (3.beta.)-: ACTIVE

Computed Properties

Molecular Weight:386.7
XLogP3:8.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:5
Exact Mass:386.354866087
Monoisotopic Mass:386.354866087
Topological Polar Surface Area:20.2
Heavy Atom Count:28
Complexity:591
Undefined Atom Stereocenter Count:8
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Synthesis Route

97838-91-0

481-14-1

212069-44-8

257939-67-6

88674-22-0

257939-67-6

Material

Cyclohexane

Ethanol

Methanol

Downstream Products

Glutaric acid

Drug Function and Efficacy

This product is a compound external ointment. Its main ingredient, ginsenoside, has the characteristics of non-ionic surface activity. It can directly enter the interior of the hair fiber and connect with the hydrophilic groups in the hair keratin through the hydroxyl groups in the ginsenoside molecules, thereby improving the tensile strength and elongation of the hair. Pepper tincture improves scalp blood circulation, and together with anti-seborrheic drugs such as diethylstilbestrol and salicylic acid, it reduces sebum secretion, increases hair follicle nutrition, improves excessive keratinization of the hair follicle mouth, and stimulates the hair growth function of the affected scalp.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Compound Ginseng Resorcinol Liniment
Ingredients	Its components are: each bottle contains 3g of ginseng tincture, 1mg of diethylstilbestrol, 1g of salicylic acid, 50mg of cholesterol, 200mg of menthol, 10mg of calcium pantothenate and other 11 flavors.
Indication	Not yet clear.
Specifications	Compound
Manufacturer	Jilin Jian Yisheng Pharmaceutical Co., Ltd.

cholesterol
Specifications	API
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Registered Holders

CARBOGEN AMCIS BV

United States
Active
Jiangsu Southeast NanoMaterials Co., Ltd.

China
Active
Hunan Er-Kang Pharmaceutical Co., Ltd.

China
Active

See More Registered Holders

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