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(-)-β-Sitosterol

(-)-β-Sitosterol structure

CAS No:
83-46-5
Formula:
C29H50O
Chemical Name:
(-)-β-Sitosterol
Synonyms:
Stigmast-5-en-3-ol,(3β)-;Stigmast-5-en-3β-ol;Nimbosterol;(3β)-Stigmast-5-en-3-ol;Cupreol;α-Dihydrofucosterol;22,23-Dihydrostigmasterol;Quebrachol;Rhamnol;β-Sitosterol;Stigmasterol,22,23-dihydro-;Angelicin (steroid);Cinchol;SKF 14463;Sitosterol;Angelicin;β-Sitosterin;24α-Ethylcholesterol;Δ5-Stigmasten-3β-ol;(24R)-Ethylcholest-5-en-3β-ol;Azuprostat;Sobatum;(-)-β-Sitosterol;(24R)-Stigmast-5-en-3β-ol;Rhammol;Sito-Lande;Harzol;α-Phytosterol;Prostasal;NSC 18173;NSC 49083;NSC 8096;Betaprost;Inmunicin MAYMO;8003-23-4;15764-35-9;76772-70-8;182512-23-8;2504119-39-3
Categories:
Cosmetic Ingredient > Emulsion Stabilising

Description

Beta-Sitosterol weakly inhibits porcine pancreatic lipase (PPL) activity. Sitosterol is an important compound extracted from the leaves of Aloe vera.

Solid

Sitosterol is a member of the class of phytosterols that is stigmast-5-ene substituted by a beta-hydroxy group at position 3. It has a role as a sterol methyltransferase inhibitor, an anticholesteremic drug, an antioxidant, a plant metabolite and a mouse metabolite. It is a 3beta-sterol, a stigmastane sterol, a 3beta-hydroxy-Delta(5)-steroid and a member of phytosterols. It derives from a hydride of a stigmastane.|Active fraction of Solanum trilobatum; reduces side-effects of radiation-induced toxicity.

(-)-β-Sitosterol Basic Attributes

Molecular Weight：

414.70700

Exact Mass：

414.71

EC Number：

201-480-6

UNII：

S347WMO6M4

NSC Number：

49083|18173|8096

DSSTox ID：

DTXSID5022481

HScode：

29061990

Characteristics

PSA：

20.23000

XLogP3：

9.3

Appearance：

Solid

Density：

0.9417 g/cm³ @ Temp: 25 °C

Melting Point：

140 °C

Boiling Point：

501.9ºC at 760 mmHg

Flash Point：

220.4ºC

Refractive Index：

1.521

Water Solubility：

H2O: INsoluble

Storage Conditions：

-20ºC

Safety Information

Packing level：

Ⅲ

Transport codes：

UN 1888 6.1/PG 3

wgk germany：

hazard class code：

R38

safety instructions：

S24/25

RTECS Number：

WJ2600000

Marks：

Precautionary statement(s)：

P201-P261-P304 + P340 + P312-P305 + P351 + P338-P308 + P313-P403 + P233

Hazard Statements：

H302-H315-H319-H331-H336-H351-H361d-H372

GHS Classification：

Not Classified

Drug Information

MeSH：

Substances that lower the levels of certain LIPIDS in the BLOOD. They are used to treat HYPERLIPIDEMIAS. (See all compounds classified as Hypolipidemic Agents.)

MeSH Entry Terms：

24-ethylcholest-5-en-3 beta-ol

(-)-β-Sitosterol Use and Manufacturing

Uses

1. A common sterol in plants. Isolated from wheat germ oil, corn oil. Antilipemic. Used in the treatment of prostatic adenoma.
2. Antiinflammatory, immunomodulator

Use Classification：

Lipids -> Sterol Lipids [ST] -> Sterols [ST01] -> Stigmasterols and C24-ethyl derivatives [ST0104]|Cosmetics -> Emulsion stabilizing; Skin conditioning; Stabilizing

Computed Properties

Molecular Weight:414.7
XLogP3:9.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:6
Exact Mass:414.386166214
Monoisotopic Mass:414.386166214
Topological Polar Surface Area:20.2
Heavy Atom Count:30
Complexity:634
Defined Atom Stereocenter Count:9
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Drug Function and Efficacy

It can quickly eliminate toxins from the body surface, have antibacterial effects, and promote the secretion of bile and pancreas.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Huangbo Capsule
Ingredients	Berberine, palmatine, phellodendronine, β-sitosterol, dithyrol.
Indication	Not yet clear
Specifications	0.33g per tablet
Manufacturer	Jiangxi Wohua Jishun Pharmaceutical Co., Ltd.

Huangbo Capsule
Ingredients	Berberine, palmatine, phellodendronine, β-sitosterol, dithyrol.
Indication	Not yet clear
Specifications	Each capsule contains 0.36 grams (equivalent to 1 gram of the original medicinal material)

Huangbo Capsule
Ingredients	Berberine, palmatine, phellodendronine, β-sitosterol, dithyrol.
Indication	Not yet clear
Specifications	Each capsule is equivalent to 1g of original medicinal material
Manufacturer	Guangdong Jiulianshan Pharmaceutical Co., Ltd.

See More Related Drugs

Registered Holders

Zhejiang Delekang Food Co., Ltd.

China
Active
Zhejiang AngLiKang Pharmaceutical Co., Ltd.

China
Active
Hangzhou Yipin Xinwufeng Pharmaceutical Co., Ltd.

China
Active

See More Registered Holders

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Guide of (-)-β-Sitosterol

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
Drug Function and Efficacy
Related Drugs
Registered Holders
Recommended Suppliers
Learn More Other Chemicals

(-)-β-Sitosterol

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