Diethyldithiocarbamic acid
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Diethyldithiocarbamic acid
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CAS No:
147-84-2
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Formula:
C5H11NS2
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Chemical Name:
Diethyldithiocarbamic acid
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Synonyms:
Carbamodithioic acid,N,N-diethyl-;Carbamic acid,diethyldithio-;Carbamodithioic acid,diethyl-;N,N-Diethylcarbamodithioic acid;Diethyldithiocarbamic acid;Diethyldithione;DIECA;N,N-Diethyldithiocarbamic acid;Diethylcarbamodithioic acid;DDC;DEDTC;NSC 1720;NSC 36546;NSC 70082;DETCA;17156-83-1;942650-37-5
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CAS No:
Description
Diethyldithiocarbamic acid is a member of the class of dithiocarbamic acids that is diethylcarbamic acid in which both of the oxygens are replaced by sulfur. It has a role as a chelator and a copper chelator. It is a conjugate acid of a diethyldithiocarbamate.|A chelating agent that has been used to mobilize toxic metals from the tissues of man and experimental animals. It is the main metabolite of DISULFIRAM.|Ditiocarb is a sulfhydryl-containing carbamate that is the primary in vivo metabolite of disulfiram. Diethyldithiocarbamate chelates zinc, thereby inhibiting metalloproteinases, thereby preventing the degradation of the extracellular matrix and inhibiting an initial step in cancer metastasis and angiogenesis. A known inhibitor of superoxide dismutase, this agent can either potentiate or protect against cell oxidative damage caused by ionizing radiation, depending on the time of administration. (NCI04)|A chelating agent that has been used to mobilize toxic metals from the tissues of humans and experimental animals. It is the main metabolite of DISULFIRAM.
Characteristics
36.3
1.6
1.079 (estimate)
143-144 °C
176.4±23.0 °C(Predicted)
1.5300 (estimate)
Soluble in alcohol
Keep container tightly closed in a dry and well-ventilated place. Hygroscopic. Store under inert gas. /Sodium diethyldithiocarbamate trihydrate/
5.9 (Air = 1)
Safety Information
Aqueous solutions decompose slowly.
P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, P501
H302
Drug Information
Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity. (See all compounds classified as Adjuvants, Immunologic.)|Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly. (See all compounds classified as Antiviral Agents.)|Chemicals that bind to and remove ions from solutions. Many chelating agents function through the formation of COORDINATION COMPLEXES with METALS. (See all compounds classified as Chelating Agents.)
Ammonium Salt Ditiocarb
Computed Properties
Molecular Weight:149.3
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:149.03329170
Monoisotopic Mass:149.03329170
Topological Polar Surface Area:36.3
Heavy Atom Count:8
Complexity:78.5
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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