Benzenesulfonamide, 4-(aminomethyl)-, hydrochloride (1:1)
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Benzenesulfonamide, 4-(aminomethyl)-, hydrochloride (1:1)
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CAS No:
138-37-4
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Formula:
C7H10N2O2S.ClH
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Chemical Name:
Benzenesulfonamide, 4-(aminomethyl)-, hydrochloride (1:1)
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Synonyms:
Benzenesulfonamide,4-(aminomethyl)-,hydrochloride (1:1);p-Toluenesulfonamide,α-amino-,monohydrochloride;Benzenesulfonamide,4-(aminomethyl)-,monohydrochloride;p-Toluenesulfonamide,α-amino-,hydrochloride;p-(Aminomethyl)benzenesulfonamide hydrochloride;p-Aminomethylphenylsulfonamide hydrochloride;α-Amino-p-toluenesulfonamide hydrochloride;4-Homosulfanilamide hydrochloride;Mafenide hydrochloride;Sulfamylon hydrochloride;Homosulfamine;Marfanil;Homosulfanilamide hydrochloride;Homosulfamine hydrochloride;p-(Aminomethyl)benzenesulfonamide monohydrochloride;4-(Aminomethyl)benzene sulfonamide monohydrochloride;4-Aminosulfonylbenzylamine hydrochloride;(4-Sulfamoylphenyl)methanaminium chloride
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CAS No:
Description
Mafenide hydrochloride is a sulfonamide-type medication used as an antibiotic.Target: AntibacterialMafenide is a sulfonamide-type medication. Mafenide works by reducing the bacterial population present in the avascular tissues of burns and permits spontaneous healing of deep partial-thickness burns. It is used to treat severe burns. It is used topically as an adjunctive therapy for second- and third-degree burns. It is bacteriostatic against many gram-positive and gram-negative organisms
Benzenesulfonamide, 4-(aminomethyl)-, hydrochloride (1:1) Basic Attributes
222.69
222.022980
205-325-3
2935009090
Benzenesulfonamide, 4-(aminomethyl)-, hydrochloride (1:1) Use and Manufacturing
General procedure: A 1.0 M solution of 4-aminobenzenesulfanilamide (17.2 g, 0.1 mol, 1.0 equiv) in acetone (100 ml) was added dropwise to a vigorously stirred suspension of cyanuric chloride (18.4 g, 1.0 equiv) in the same solvent (100 ml) at 0 C. The white slurry was stirred at the same temperature for 30 min. and then a 1.7 M aqueous solution of NaOH (4.0 g, 1.0 equiv) was added over a period of 20 min. Stirring was continued for 1 h, the reaction was quenched by addition of slush (100 ml) and the solid filtered off.
Antibacterial;Inhibitor of folic acid biosynthesis
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