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Phenibut

Phenibut structure

CAS No:
1078-21-3
Formula:
C10H13NO2
Chemical Name:
Phenibut
Synonyms:
Benzenepropanoic acid,β-(aminomethyl)-;Hydrocinnamic acid,β-(aminomethyl)-;β-(Aminomethyl)benzenepropanoic acid;Phenigam;Phenygam;β-Phenyl-γ-aminobutyric acid;4-Amino-3-phenylbutyric acid;γ-Amino-β-phenylbutyric acid;Fenibut;Phenybut;β-Phenyl-GABA;Fenigam;Fenigama;PhGABA;Phenibut;P-GABA;DL-β-Phenyl-γ-aminobutyric acid;DL-4-Amino-3-phenylbutanoic acid;(±)-β-Phenyl-GABA;(±)-Fenibut;3-Phenyl-4-aminobutanoic acid;Anvifen;4-Amino-3-phenylbutanoic acid;35568-37-7
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

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Description

Phenibut is an organonitrogen compound and an organooxygen compound. It derives from a gamma-amino acid.

Phenibut Basic Attributes

Molecular Weight：

215.68

Exact Mass：

179.22

EC Number：

214-079-6

ATC Code：

N - Nervous system

HScode：

2922499990

Characteristics

PSA：

63.32000

XLogP3：

2.70590

Melting Point：

253 °C (decomp)

Safety Information

Hazard category：

IRRITANT

Marks：

Precautionary statement(s)：

P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501

Hazard Statements：

H315

GHS Classification：

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 3 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH：

Drugs used to prevent SEIZURES or reduce their severity. (See all compounds classified as Anticonvulsants.)|Drugs used to induce drowsiness or sleep or to reduce psychological excitement or anxiety. (See all compounds classified as Hypnotics and Sedatives.)|Endogenous compounds and drugs that bind to and activate GAMMA-AMINOBUTYRIC ACID receptors (RECEPTORS, GABA). (See all compounds classified as GABA Agonists.)|Substances that act in the brain stem or spinal cord to produce tonic or clonic convulsions, often by removing normal inhibitory tone. They were formerly used to stimulate respiration or as antidotes to barbiturate overdose. They are now most commonly used as experimental tools. (See all compounds classified as Convulsants.)|A traditional grouping of drugs said to have a soothing or calming effect on mood, thought, or behavior. Included here are the ANTI-ANXIETY AGENTS (minor tranquilizers), ANTIMANIC AGENTS, and the ANTIPSYCHOTIC AGENTS (major tranquilizers). These drugs act by different mechanisms and are used for different therapeutic purposes. (See all compounds classified as Tranquilizing Agents.)

MeSH Entry Terms：

4-amino-3-phenylbutyric acid

Phenibut Use and Manufacturing

Uses

Used as an antidepressant

Manufacturing Info：

Benzenepropanoic acid, .beta.-(aminomethyl)-: INACTIVE

Computed Properties

Molecular Weight:179.22
XLogP3:-1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:179.094628657
Monoisotopic Mass:179.094628657
Topological Polar Surface Area:63.3
Heavy Atom Count:13
Complexity:164
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes