Cinanserin
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Cinanserin
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CAS No:
1166-34-3
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Formula:
C20H24N2OS
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Chemical Name:
Cinanserin
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Synonyms:
2-Propenamide,N-[2-[[3-(dimethylamino)propyl]thio]phenyl]-3-phenyl-;Cinnamanilide,2′-[[3-(dimethylamino)propyl]thio]-;N-[2-[[3-(Dimethylamino)propyl]thio]phenyl]-3-phenyl-2-propenamide;Cinanserin;2′-[[3-(Dimethylamino)propyl]thio]cinnamanilide;Cinanserine
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CAS No:
Description
Cinanserin is an aryl sulfide that is (2E)-3-phenyl-N-(2-sulfanylphenyl)prop-2-enamide in which the hydrogen of the thiol group is substituted by a 3-(dimethylamino)propyl group. It is a 5-hydroxytryptamine receptor antagonist and an inhibitor of SARS-CoV replication. It has a role as an EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor, an antiviral agent and an anticoronaviral agent. It is a tertiary amino compound, a secondary carboxamide, a member of cinnamamides and an aryl sulfide. It is a conjugate base of a cinanserin(1+).|A serotonin antagonist with limited antihistaminic, anticholinergic, and immunosuppressive activity.
Safety Information
P264, P270, P301+P312, P330, P501
H302
|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P301+P312, P330, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Drug Information
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or SEROTONIN RECEPTOR AGONISTS. (See all compounds classified as Serotonin Antagonists.)
Cinanserin
Computed Properties
Molecular Weight:340.5
XLogP3:4.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:8
Exact Mass:340.16093457
Monoisotopic Mass:340.16093457
Topological Polar Surface Area:57.6
Heavy Atom Count:24
Complexity:391
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes