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Home > Encyclopedia > 5-Hydroxy-3,7,3′,4′-tetramethoxyflavone

5-Hydroxy-3,7,3′,4′-tetramethoxyflavone

5-Hydroxy-3,7,3′,4′-tetramethoxyflavone structure

5-Hydroxy-3,7,3′,4′-tetramethoxyflavone 

structure
  • CAS No:

    1245-15-4

  • Formula:

    C19H18O7

  • Chemical Name:

    5-Hydroxy-3,7,3′,4′-tetramethoxyflavone

  • Synonyms:

    4H-1-Benzopyran-4-one,2-(3,4-dimethoxyphenyl)-5-hydroxy-3,7-dimethoxy-;Flavone,5-hydroxy-3,3′,4′,7-tetramethoxy-;2-(3,4-Dimethoxyphenyl)-5-hydroxy-3,7-dimethoxy-4H-1-benzopyran-4-one;Retusin (Ariocarpus);Retusine;Quercetin 3,7,3′,4′-tetramethyl ether;Retusin;3,3′,4′,7-Tetramethylquercetin;5-Hydroxy-3,3′,4′,7-tetramethoxyflavone;5-Hydroxy-3,7,3′,4′-tetramethoxyflavone;NSC 61837;NSC 618937;Quercetin 3,3′,4′,7-O-tetramethyl ether;3,3′,4′,7-Tetra-O-methylquercetin;2-(3,4-Dimethoxyphenyl)-5-hydroxy-3,7-dimethoxy-4H-chromen-4-one

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

Description

Retusin (Quercetin-3,3',4',7-tetramethylether), a natural compound isolated from the leaves of Talinum triangulare, possesses antiviral and anti-inflammatory activities[1].


5-hydroxy-3,3',4',7-tetramethoxyflavone is a monohydroxyflavone that is 5-hydroxyflavone which is substituted by methoxy groups at positions 3,3',4' and 7. It has a role as a plant metabolite. It is a tetramethoxyflavone, a member of 3'-methoxyflavones and a monohydroxyflavone. It is a conjugate acid of a 5-hydroxy-3,3',4',7-tetramethoxyflavone(1-).

5-Hydroxy-3,7,3′,4′-tetramethoxyflavone Basic Attributes

358.34200

358.34

214-991-4

M8591903SD

618937|61837

2914509090

Characteristics

87.36000

3.20000

1.36g/cm3

159-160 °C

569.2ºC at 760mmHg

205.6ºC

1.617

1.48E-13mmHg at 25°C

180.8 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Drug Information

5-hydroxy-3,7,3',4'-tetramethoxyflavone

5-Hydroxy-3,7,3′,4′-tetramethoxyflavone Use and Manufacturing

Polyketides [PK] -> Flavonoids [PK12] -> Flavones and Flavonols [PK1211]

Computed Properties

Molecular Weight:358.3
XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:358.10525291
Monoisotopic Mass:358.10525291
Topological Polar Surface Area:83.4
Heavy Atom Count:26
Complexity:546
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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