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Home > Encyclopedia > 3-oxo-4-aza-5A-androstane-17B-(N-T-butylcarboxamoyl)

3-oxo-4-aza-5A-androstane-17B-(N-T-butylcarboxamoyl)

pharmaceutical raw materials
3-oxo-4-aza-5A-androstane-17B-(N-T-butylcarboxamoyl) structure

3-oxo-4-aza-5A-androstane-17B-(N-T-butylcarboxamoyl) 

structure
  • CAS No:

    98319-24-5

  • Formula:

    C23H38N2O2

  • Chemical Name:

    3-oxo-4-aza-5A-androstane-17B-(N-T-butylcarboxamoyl)

  • Synonyms:

    17β-(N-tert-Butylcarbamoyl)-4-aza-5α-androstan-3-one;3-Oxo-4-Aza-5A-Androstane-17B-(N-T-Butyl)Carboxamide;(4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-tert-butyl-4a,6a-dimethyl-2-oxohexadecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide;Androstane-N-terbutyl-3-oxo-4-aza-5 alfa-17 beta-carboxamide;17-beta-(n-butylcarbamoyl)-4-aza-5-alpha-androstan-3-one;17β-(t-Butylcarbamoyl)-4-aza-5a-androstan-3-one;Dihydroproscar;N-tert-butyl-3-oxo-4-aza-5α-androst-17β-carboxamide;

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

Description

White Solid

3-oxo-4-aza-5A-androstane-17B-(N-T-butylcarboxamoyl) Basic Attributes

374.560

374.293335

DTXSID40432068

29242990

Characteristics

58.20000

3.00

1.1±0.1 g/cm3

273-275 °C

569.4±49.0 °C at 760 mmHg

171.7±30.0 °C

1.514

Safety Information

NONH for all modes of transport

3

R36/37/38

26-36

Xi

P201, P202, P261, P264, P270, P271, P280, P281, P301+P312, P302+P352, P304+P340, P305+P351+P338, P308+P313, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, P501

H302

|Warning|H302 (33.33%): Harmful if swallowed [Warning Acute toxicity, oral]|P201, P202, P261, P264, P270, P271, P280, P281, P301+P312, P302+P352, P304+P340, P305+P351+P338, P308+P313, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 3 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

3-oxo-4-aza-5A-androstane-17B-(N-T-butylcarboxamoyl) Use and Manufacturing

The reduced product of Finasteride (F342000): a mechanism-based inhibitor of human prostate and skin steroid 5α-reductase. It forms an enzyme-bound NADP-dihydrofinasteride adduct during this inhibitor y process.

Computed Properties

Molecular Weight:374.6
XLogP3:4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:374.293328459
Monoisotopic Mass:374.293328459
Topological Polar Surface Area:58.2
Heavy Atom Count:27
Complexity:639
Defined Atom Stereocenter Count:7
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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