4-Fluoro-3-phenoxybenzaldehyde
-
4-Fluoro-3-phenoxybenzaldehyde
structure -
-
CAS No:
68359-57-9
-
Formula:
C13H9FO2
-
Chemical Name:
4-Fluoro-3-phenoxybenzaldehyde
-
Synonyms:
Benzaldehyde,4-fluoro-3-phenoxy-;4-Fluoro-3-phenoxybenzaldehyde;3-Phenoxy-4-fluorobenzaldehyde
- Categories:
-
CAS No:
Safety Information
9
UN 3082 9/PG 3
2
22-51/53
61
Xn,N
Harmful
P273-P301 + P312 + P330-P391-P501
H302-H411
|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P280, P301+P312, P305+P351+P338, P330, P337+P313, and P501|Aggregated GHS information provided by 40 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
4-Fluoro-3-phenoxybenzaldehyde Use and Manufacturing
The preparation methods reported in the literature have the following methods. Use fluorobenzene as raw material. The above methods using p-toluidine as raw material and p-chlorotoluene as raw material have certain shortcomings. They are either long process routes, low yields, many wastes, and difficult industrialization. Industrial preparation is to use p-fluorobenzaldehyde as a raw material, first bromination with bromine to obtain 3-bromo-4-fluorobenzaldehyde, and further condensation with phenol must be carried out under alkaline conditions, and under alkaline conditions, 3- Bromo-4-fluorobenzaldehyde is prone to Conicaro reaction to generate the corresponding acid and alcohol. For this reason, the aldehyde group must be protected, protected with ethylene glycol to generate acetal, and then etherified with sodium phenolate. Finally, hydrolysis is performed to obtain 3-phenoxy-4-fluorobenzaldehyde.
3-Phenoxy-4-fluorobenzaldehyde is an important intermediate for pyrethroids such as cyfluthrin, budesin, cyfluthrin and hydrocarbon pyrethrins.
Benzaldehyde, 4-fluoro-3-phenoxy-: ACTIVE|PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.
Computed Properties
Molecular Weight:216.21
XLogP3:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:216.05865769
Monoisotopic Mass:216.05865769
Topological Polar Surface Area:26.3
Heavy Atom Count:16
Complexity:226
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of 4-Fluoro-3-phenoxybenzaldehyde
-
![China]()
CN
5 YRS
Business licensed Certified factoryManufactory Supplier of fine chemicals,pharmaceutical materials -
![China]()
CN
5 YRS
Business licensed Certified factoryManufactory Supplier of Pharmaceutical intermedaite,Agricultural chemical intermediateInquiryCAS No.: 68359-57-9Grade: Agricultural GradeContent: 99.0%
Learn More Other Chemicals
-
1-phenyl-3-(1H-1,2,4-triazol-5-yl)urea
55424-82-3
-
Bromopyruvic acid
1113-59-3
-
2-Amino-5-chlorophenol
28443-50-7
-
N-[2-(2,4,6-Trichlorophenoxy)ethyl]-1-propanamine Formula
67747-01-7
-
2-(4-chlorophenyl)-2-methylpropanol Formula
80854-14-4
-
1,6-Hexanediol Formula
629-11-8
-
4-Morpholinamine Structure
4319-49-7
-
S-Octyl carbonochloridothioate Structure
13889-96-8
-
What is 2-(2-Bromoethoxy)-1,3,5-trichlorobenzene
26378-23-4
-
What is 2,4′-Difluorobenzophenone
342-25-6