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Home > Active Pharmaceutical Ingredients > Antiparasitic Drugs (Find 4 items)

Antiparasitic Drugs

Salinomycin

(53003-10-4)
Salinomycin is a polyether ionophore with broad spectrum Gram positive and anti-coccidial activity. Salinomycin has a high affinity for monovalent cations, particularly potassium. Salinomycin is used to control coccidia in animals and for growth promotion in ruminants. Recently, salinomycin has been shown to inhibit cancer stem cells and is >100 times more potent than taxol. While the mechanism of action is unknown, it was noted that among the 60,000 compounds screened, another monovalent ionoph

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Sulfaclozine

(102-65-8)
Sulfonamide antibacterials, used for the infection of Escherichia coli and Bacillus of livestock and poultry. Compounded with trimethoprim and sucrose, the compound sulfachloropyridazine sodium salt is more effective. Those who are allergic to sulfonamides are contraindicated, and those with impaired renal function Use with caution.

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Salinomycin sodium

(55721-31-8)
Salinomycin sodium is prepared from salinomycin taking advantage of the acidic carboxylic acid which ionises and readily forms the salt in sodium hydroxide solutions. The sodium salt is the preferred formulation in animals to prevent coccidiosis and to promote growth. Salinomycin has a high affinity for monovalent cations, particularly potassium. Recently, salinomycin has been shown to inhibit cancer stem cells.

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Sodium stibogluconate

(16037-91-5)
Sodium stibogluconate is a pentavalent antimony derivative that is highly active against Leishmania amastigotes in macrophages. Sodium stibogluconate has diverse effects on both this intracellular parasite and its host cell.

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Parasitic diseases can be divided into protozoan diseases and helminthiasis. Protozoan diseases include malaria, amoebiasis, leishmaniasis, etc., helminthiasis includes flukes, filariasis and nematodes, etc. Therefore, antiparasitic drugs can be divided into antiprotozoal drugs and antihelminthic drugs. The "ECHEMI Antiparasitic Drugs" list mainly supplies APIs for such drugs.

Frequently Asked Questions

What are antiparasitic drugs used for?

Antiparasitic drugs are medications designed to treat infections caused by parasites, including protozoa, helminths (worms), and ectoparasites like lice and mites. These drugs work by either killing the parasites or inhibiting their growth and reproduction. Common conditions treated with antiparasitics include malaria, giardiasis, schistosomiasis, and scabies. Choosing the right antiparasitic depends on the specific parasite involved and the patient’s health profile.

How do I choose a reliable supplier of antiparasitic drugs?

To choose a reliable supplier of antiparasitic drugs, consider the following criteria:1. Regulatory compliance—ensure the supplier holds certifications such as WHO-GMP, FDA approval, or ISO standards.2. Quality assurance—verify that they conduct rigorous testing for purity, potency, and stability.3. Manufacturing transparency—reputable suppliers provide documentation on sourcing, synthesis, and batch records.4. Global distribution experience—especially important for bulk buyers needing consistent supply chains.Evaluating these factors helps ensure safe, effective, and compliant antiparasitic products.

What are the common types of antiparasitic medications?

Antiparasitic medications are broadly categorized based on the type of parasite they target:1. Antiprotozoals (e.g., metronidazole, chloroquine) for protozoan infections like malaria and trichomoniasis.2. Anthelmintics (e.g., albendazole, ivermectin) for worm infestations such as roundworms and tapeworms.3. Ectoparasiticides (e.g., permethrin, lindane) for external parasites like lice and scabies mites.Each class has distinct mechanisms of action and is selected based on accurate diagnosis and treatment guidelines.

Are generic antiparasitic drugs as effective as branded ones?

Yes, generic antiparasitic drugs are generally as effective as their branded counterparts when they are approved by recognized regulatory authorities such as the FDA or EMA. Generics must demonstrate bioequivalence—meaning they deliver the same active ingredient at the same rate and concentration in the body. However, quality can vary among manufacturers, so it’s essential to source generics from certified, reputable suppliers with strong quality control systems.

What quality standards should antiparasitic drugs meet?

Antiparasitic drugs must comply with international pharmaceutical quality standards to ensure safety and efficacy. Key requirements include:1. Adherence to Good Manufacturing Practices (GMP) as defined by the WHO or relevant national agencies.2. Compliance with pharmacopeial standards (e.g., USP, EP, BP) for identity, assay, impurities, and dissolution.3. Stability testing under ICH guidelines to guarantee shelf life.4. Proper labeling and documentation for traceability.Meeting these standards is critical for both human and veterinary antiparasitic formulations.

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