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Home > Active Pharmaceutical Ingredients > Antiparasitic Drugs (Find 20 items)

Antiparasitic Drugs

Piperazine

(110-85-0)
keratolytic, antiseborheic

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Praziquantel

(55268-74-1)
Anthelmintic, effective against flatworms.

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Phenothiazine

(92-84-2)
Insecticide; manufacture of pharmaceuticals.Phenothiazine is a more widely used anthelmintic, which has good effects on gastric contortus, nodular worms, nematodes, and Xia's nematodes in cattle, horses and sheep.

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Pyrimethamine

(58-14-0)
Dihydrofolate reductase inhibitor; generally used in combination with other antimicrobial agents. Antiprotozoal (Toxoplasma); antimalarial This product can inhibit dihydrofolate reductase, so that dihydrofolate cannot be converted into tetrahydrofolate, which leads to the reduction of nucleic acid synthesis and inhibits the reproduction of malaria parasites. It is mainly used to prevent malaria. It can also be combined with primaquine to prevent malaria from recurring.

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Primaquine

(90-34-6)
It has a strong insecticidal effect on Plasmodium vivax in the infrared period and various gametophyte types, and is an effective drug for eradicating P. vivax and blocking the transmission of various types of malaria. Primaquine has a weak effect on the erythrozoan schizonts and is not effective against the erythrozoan schizonts of Plasmodium falciparum. Therefore, it cannot be used to control symptoms. It is used to control the recurrence and spread of P. vivax and P. malaria and to prevent th

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Primaquine diphosphate

(63-45-6)
Primaquine is an established antimalarial drug used in the treatment of persistent liver forms of P. vivax or P. ovale infection for its ability to kill late-stage gametocytes and hypnozoites. In historical terms, this aminoquinoline was the stimulus for the discovery of glucose-6-phosphate (G6P) dehydrogenase deficiency as it induced hemolytic anemia in patients lacking the G6P-metabolizing enzyme.

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Piperazine adipate

(142-88-1)
It is used as an anthelmintic for humans and farm animals against intestinal roundworms and pinworms infection

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Parasitic diseases can be divided into protozoan diseases and helminthiasis. Protozoan diseases include malaria, amoebiasis, leishmaniasis, etc., helminthiasis includes flukes, filariasis and nematodes, etc. Therefore, antiparasitic drugs can be divided into antiprotozoal drugs and antihelminthic drugs. The "ECHEMI Antiparasitic Drugs" list mainly supplies APIs for such drugs.

Frequently Asked Questions

What are antiparasitic drugs used for?

Antiparasitic drugs are medications designed to treat infections caused by parasites, including protozoa, helminths (worms), and ectoparasites like lice and mites. These drugs work by either killing the parasites or inhibiting their growth and reproduction. Common conditions treated with antiparasitics include malaria, giardiasis, schistosomiasis, and scabies. Choosing the right antiparasitic depends on the specific parasite involved and the patient’s health profile.

How do I choose a reliable supplier of antiparasitic drugs?

To choose a reliable supplier of antiparasitic drugs, consider the following criteria:1. Regulatory compliance—ensure the supplier holds certifications such as WHO-GMP, FDA approval, or ISO standards.2. Quality assurance—verify that they conduct rigorous testing for purity, potency, and stability.3. Manufacturing transparency—reputable suppliers provide documentation on sourcing, synthesis, and batch records.4. Global distribution experience—especially important for bulk buyers needing consistent supply chains.Evaluating these factors helps ensure safe, effective, and compliant antiparasitic products.

What are the common types of antiparasitic medications?

Antiparasitic medications are broadly categorized based on the type of parasite they target:1. Antiprotozoals (e.g., metronidazole, chloroquine) for protozoan infections like malaria and trichomoniasis.2. Anthelmintics (e.g., albendazole, ivermectin) for worm infestations such as roundworms and tapeworms.3. Ectoparasiticides (e.g., permethrin, lindane) for external parasites like lice and scabies mites.Each class has distinct mechanisms of action and is selected based on accurate diagnosis and treatment guidelines.

Are generic antiparasitic drugs as effective as branded ones?

Yes, generic antiparasitic drugs are generally as effective as their branded counterparts when they are approved by recognized regulatory authorities such as the FDA or EMA. Generics must demonstrate bioequivalence—meaning they deliver the same active ingredient at the same rate and concentration in the body. However, quality can vary among manufacturers, so it’s essential to source generics from certified, reputable suppliers with strong quality control systems.

What quality standards should antiparasitic drugs meet?

Antiparasitic drugs must comply with international pharmaceutical quality standards to ensure safety and efficacy. Key requirements include:1. Adherence to Good Manufacturing Practices (GMP) as defined by the WHO or relevant national agencies.2. Compliance with pharmacopeial standards (e.g., USP, EP, BP) for identity, assay, impurities, and dissolution.3. Stability testing under ICH guidelines to guarantee shelf life.4. Proper labeling and documentation for traceability.Meeting these standards is critical for both human and veterinary antiparasitic formulations.

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