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    Home > Chemial News > > Current status and development of cosmetic efficacy evaluation in 2020

    Current status and development of cosmetic efficacy evaluation in 2020

    Echemi 2020-09-09

    With the increasing diversification of consumer demand, the cosmetics industry is developing rapidly, and relevant laws and regulations have also undergone major changes, becoming more rigorous and comprehensive. At the same time, as an important part of cosmetic product quality control, the importance of cosmetic efficacy evaluation research has become increasingly prominent, and it has become a hot spot for cosmetic companies and research institutions around the world.


    1. The concept of cosmetics

    In response to the rapid development of the cosmetics industry and the refinement of industry classification, my country's cosmetics regulations are also undergoing tremendous changes. In June 2020, the "Regulations on the Supervision and Administration of Cosmetics" (hereinafter referred to as the "Regulations") was officially released. In the "Regulations", the definition of cosmetics has been adjusted: cosmetics refer to the daily application of skin, hair, nails, lips and other human surfaces by rubbing, spraying or other similar methods for the purpose of cleaning, protecting, beautifying and modifying. Use chemical industry products. At the same time, it is also clear that toothpaste shall be managed in accordance with the regulations on ordinary cosmetics. After the definition adjustment, the composition of cosmetic products will change, the category of cosmetics will increase significantly, and the market’s focus on the quality of cosmetics will increase. The scope of target substances for future efficacy evaluation and testing will also change accordingly. The requirements will be higher and higher.

     

    2. Main methods of cosmetic efficacy evaluation

    The efficacy evaluation of cosmetics is a combination of physics, chemistry, biochemistry, biophysics, dermatology, imaging and other disciplines, using scientific analysis and testing methods, combining human aesthetics and ethics, and applying biostatistics. , A discipline that evaluates the efficacy of cosmetics. At present, the efficacy evaluation methods of cosmetics at home and abroad mainly include human body method and in vitro method.


    (1) Human body law

    Human body method is currently the most widely used method in cosmetic efficacy evaluation technology. It mainly includes expert panel evaluation, consumer self-evaluation and biophysical evaluation.

    The expert panel evaluation is mainly to evaluate the effects of cosmetics through visual, tactile and olfactory perception, such as smell, smoothness, etc., or according to certain scoring standards, the improvement of the skin color and skin wrinkles of the subjects before and after using the product Make an evaluation. This method is highly subjective and has high requirements for evaluators. It requires continuous training for evaluators to ensure the repeatability of their evaluation results. Expert evaluation is usually based on skin, ophthalmology or dentistry doctors and experts.

    Consumer self-evaluation is to take consumers as the research object, collect consumers' feedback on product odor, skin feel, touch, taste and other related characteristics through consumer trials and questionnaire surveys, and then combine the results of questionnaire survey statistics , To evaluate the efficacy of cosmetics. This method can obtain the most intuitive feelings and evaluations of consumers about the product. Through data statistics and analysis, the corresponding efficacy of the product can be directly supported. However, in order to avoid the influence of strong subjectivity on the results, the design of the questionnaire is also relatively high. Requirements.

    Biophysical methods are currently the most widely used and objective technical methods in domestic and foreign industries, including instrumental measurement methods and imaging analysis methods. This method can not only obtain objective and quantitative detection data, but also provide proof for product efficacy claims through intuitive and visual images. At present, with the upgrading of equipment, the excavation of skin science and product action mechanism, and the development of image analysis technology, the non-invasive detection of skin surface parameters to deep skin cell morphology can be achieved through biophysical evaluation methods. The leap from the skin level to the cell level. For example, at the epidermal level, testing equipment or imaging equipment can detect the surface moisture, oil, desquamation, wrinkles and other biophysical indicators of the skin; in the deep skin, it can observe the stratum corneum and dermis morphology, protein, etc. Detection of component structure, detection of skin cell morphology and structure, and quantitative detection of deep skin moisture, protein content, pigment content, and penetration of exogenous components in the skin.


    (2) In vitro method

    In vitro evaluation methods mainly refer to the evaluation of cosmetic efficacy by techniques such as physical and chemical methods, biochemical methods, cell biology methods, and tissue model alternative methods.

    Physical and chemical methods are mainly used in the evaluation of cosmetic moisturizing and sunscreen efficacy. Calculate and characterize the sunscreen effect of the sunscreen product through the absorption and transmittance of ultraviolet rays. This type of method is simple to operate and the results are reproducible.

    Biochemical methods and cell biology methods are mainly applied in the field of anti-aging and anti-oxidation evaluation of cosmetics. With the help of spectroscopic analysis and chemical analysis, the hydroxyl radical scavenging and superoxide anion inhibition capabilities are tested or the tyrosinase inhibition capability is tested. This kind of method is mainly suitable for evaluating the efficacy of cosmetic raw materials. In addition, human or animal cells can be cultured in vitro to construct cell models, and the efficacy of cosmetic raw materials can be characterized by colorimetry or combined with enzyme-linked immunoassay and other technical means. For example, by detecting the ability of cosmetic raw materials to inhibit melanin production of cells and inhibit tyrosinase activity, the whitening effect of raw materials can be evaluated.

    The tissue model method is an important example of the application of bioengineering technology in the field of cosmetic efficacy evaluation. The three-dimensional human skin model constructed by this technology simulates human skin in terms of gene expression, metabolic vitality, tissue structure, etc. It can also construct skin models containing different skin structures according to testing needs, such as in vitro hair follicle culture system, three-dimensional melanin skin model Wait. The application in the evaluation of hair cosmetics/raw materials and the evaluation of whitening efficacy is of great significance. In addition, isolated tissues and organs are also an important basis for the evaluation of cosmetic efficacy. For example, the efficacy evaluation of hair cosmetics usually uses isolated hair as the research object, observes the microstructure of hair fibers through microscopic imaging technology, and detects the ductility, breaking strain, tensile performance, and combing performance of the hair. Evaluate the effects of cosmetics, mechanical damage, dryness, etc. on hair.


    3. Current status of efficacy evaluation of cosmetics at home and abroad

    In recent years, with the continuous development of my country's cosmetics industry, the research on the efficacy evaluation technology of cosmetics has become more and more in-depth, and the gap with international advanced technology has become smaller and smaller.

    In the context of the early start of the cosmetics industry, developed countries such as Europe and the United States have always been in the forefront of the world in the supervision of product efficacy. With the advantages of skin science research and mechanical equipment development technology, the corresponding efficacy evaluation technology and equipment of cosmetics are relatively mature, leading the development of the industry. In terms of non-invasive testing methods for the efficacy of cosmetics, a number of guidance methods and guidelines have been issued, and relevant research results have been published in various industry key journals. For example, EEMCO (European Cosmetics and Other Commodity Effectiveness Evaluation Expert Agency) has issued a number of clinical evaluation technical guidelines for the detection of skin biophysical parameters, including skin color test, skin gloss test, moisture content test, skin Barrier function test, hair product efficacy test, etc., provide support for the product's comprehensive effects such as whitening, moisturizing, and anti-wrinkle. For many years, such methods have been the main basis for reference in the industry. In addition, various countries have successively established standard methods for evaluating the efficacy of sunscreen cosmetics, such as JCIA standard methods and FDA standard methods. Among them, standard methods related to sun protection have also been included in ISO standards.

    Although my country has established a series of method standards for the evaluation of cosmetic efficacy, they are limited to sunscreen and moisturizing products. The standardization of methods still needs to be improved. For example, in 2011, the Ministry of Industry and Information Technology issued my country's first guidelines for cosmetic efficacy evaluation methods, namely, the light industry standard QB/T4256-2011 cosmetic moisturizing efficacy evaluation guidelines. This guide was jointly drafted by the Chinese Academy of Inspection and Quarantine Sciences, Beijing Technology and Business University, and the PLA Air Force General Hospital. It is used to standardize the method of evaluating cosmetic moisturizing efficacy and is the most basic standard referenced in the current cosmetic moisturizing efficacy evaluation. In addition, the method for measuring the SPF value of sunscreen cosmetics, the method for measuring the long-wave ultraviolet protection index (PFA value) of sunscreen cosmetics, and the method for measuring the waterproof performance of sunscreen cosmetics included in my country's "Cosmetics Safety Technical Specifications" (2015 edition) are also the earliest in my country Efficacy evaluation method standard. In 2019, the General Administration of Customs issued the entry-exit inspection and quarantine industry standard "SN/T5150-2019 Sunscreen Cosmetics UVA Photoprotective Effect In Vitro Test Method", which is equivalent to quoting ISO24443, which was formally implemented in May 2020. This standard is an important translation and quotation of my country’s international evaluation standards for cosmetic efficacy evaluation. The release of this standard indicates that my country’s sunscreen cosmetic efficacy evaluation system has achieved a breakthrough in the field of in vitro research. It will also greatly improve the detection efficiency of cosmetics and effectively Cosmetics supervision provides technical support. After oral care products are placed under the management of the cosmetics system, the current health industry standard WS/T3236.1-2010 issued in 2010 is still applicable, mainly stipulating anti-caries, inhibiting dental plaque and/or reducing gum inflammation , Anti-dentin sensitivity and other methods, this set of standard methods has also become an important part of the standardization of my country’s cosmetic efficacy evaluation system.

    In addition, my country's cosmetics companies and related organizations are also actively establishing internal standardized technical methods, which is of great significance for improving my country's cosmetic efficacy evaluation system. For example, Zhejiang Health Products and Cosmetics Industry Association and Proya Cosmetics Co., Ltd. have jointly formulated and issued "T/ZHCA001-2018 Cosmetics Whitening and Freckle Efficacy Test Method", "T/ZHCA002-2018 Cosmetics Oil Control Efficacy Test Method" and "T/ ZHCA003-2018 Cosmetics influence transepidermal moisture loss test method" "T/ZHCA004-2018 Cosmetics influence skin surface pH test method" "T/ZHCA005-2019 cosmetics influence skin elasticity test method" "T/ZHCA006-2019 Cosmetics anti-wrinkle efficacy test method 》And other group standards, the Shanghai Daily Chemical Industry Association has formulated a clinical evaluation method standard for the efficacy of cosmetics in improving eye lines. Although such standards are voluntary standards adopted by the society and are not compulsory, they can play a leading role in market orientation and industry self-discipline in the industry field.


    4. Regulatory requirements for cosmetic efficacy evaluation

    At present, my country's cosmetics industry is showing the characteristics of multimorphic development, and the flexible switching of product sales models, especially the integration of Internet platforms and e-commerce platforms, has brought huge challenges to the supervision of product and raw material traceability. In order to effectively deal with these challenges, a number of cosmetics regulatory policies in my country have undergone major adjustments this year. In the "Regulations on Supervision and Administration of Cosmetics" issued in June 2020, the original classification of "special use cosmetics" and "non-special use cosmetics" was adjusted to "special cosmetics" and "ordinary cosmetics" based on product names and risk classifications. , And clarified the management and management requirements for the registration and filing of each type of product. At the same time, in July 2020, the National Food and Drug Administration issued the "Specifications for Classification of Cosmetics" (draft for comments), which classified cosmetics into 28 categories, including cleansing, makeup remover, moisturizing, and moisturizing, according to their efficacy claims, parts of action, dosage forms, and users. , The classification is more refined. In the "Guiding Principles for the Evaluation of Cosmetic Efficacy Claims (Draft for Comment)", the evaluation principles and standard testing methods for various efficacies are defined. We can see that my country has stricter supervision of cosmetics and more focused supervision.


    V. Outlook

    In our country, cosmetics efficacy evaluation still has a high dependence on instruments and equipment, and very few companies have scientific efficacy evaluation knowledge, complete efficacy testing equipment and standardized evaluation technology. Most companies rely on third-party testing institutions. Carry out strict cosmetic efficacy evaluation. In contrast, when the functional cosmetics of well-known foreign companies enter the Chinese market, they will conduct internal evaluations and compare them with the evaluation results of third-party testing agencies to confirm the consistency of the results of both parties and ensure the reliability of the evaluation results of functional cosmetics . In this regard, there are still some gaps between Chinese cosmetics companies and international companies. But on the other hand, under the impact of the information age, the development of big data and computer technology, the application of artificial intelligence technology in the field of cosmetic efficacy evaluation in my country has also formed my country's unique advantages and characteristics. At present, my country's cosmetics efficacy evaluation has made great progress in the automation and portability of related equipment, and the scientific, comprehensive, and comprehensive efficacy evaluation results have also been greatly improved, which fully reflects the new creativity of my country's cosmetics industry .

    Therefore, in order to promote the overall level of cosmetic efficacy evaluation in my country in the future, it is necessary for cosmetic companies and related practitioners to use the advantages of continuous technological innovation to jointly advance from various perspectives such as equipment, inspection skills, and training of high-quality inspectors to establish a comprehensive The cosmetic efficacy evaluation system promotes the safe and healthy development of my country's functional cosmetics.

    . At the same time, as an important part of cosmetic product quality control, the importance of cosmetic efficacy evaluation research has become increasingly prominent, and it has become a hot spot for cosmetic companies and research institutions around the world.


    1. The concept of cosmetics

    In response to the rapid development of the cosmetics industry and the refinement of industry classification, my country's cosmetics regulations are also undergoing tremendous changes. In June 2020, the "Regulations on the Supervision and Administration of Cosmetics" (hereinafter referred to as the "Regulations") was officially released. In the "Regulations", the definition of cosmetics has been adjusted: cosmetics refer to the daily application of skin, hair, nails, lips and other human surfaces by rubbing, spraying or other similar methods for the purpose of cleaning, protecting, beautifying and modifying. Use chemical industry products. At the same time, it is also clear that toothpaste shall be managed in accordance with the regulations on ordinary cosmetics. After the definition adjustment, the composition of cosmetic products will change, the category of cosmetics will increase significantly, and the market’s focus on the quality of cosmetics will increase. The scope of target substances for future efficacy evaluation and testing will also change accordingly. The requirements will be higher and higher.

     

    2. Main methods of cosmetic efficacy evaluation

    The efficacy evaluation of cosmetics is a combination of physics, chemistry, biochemistry, biophysics, dermatology, imaging and other disciplines, using scientific analysis and testing methods, combining human aesthetics and ethics, and applying biostatistics. , A discipline that evaluates the efficacy of cosmetics. At present, the efficacy evaluation methods of cosmetics at home and abroad mainly include human body method and in vitro method.


    (1) Human body law

    Human body method is currently the most widely used method in cosmetic efficacy evaluation technology. It mainly includes expert panel evaluation, consumer self-evaluation and biophysical evaluation.

    The expert panel evaluation is mainly to evaluate the effects of cosmetics through visual, tactile and olfactory perception, such as smell, smoothness, etc., or according to certain scoring standards, the improvement of the skin color and skin wrinkles of the subjects before and after using the product Make an evaluation. This method is highly subjective and has high requirements for evaluators. It requires continuous training for evaluators to ensure the repeatability of their evaluation results. Expert evaluation is usually based on skin, ophthalmology or dentistry doctors and experts.

    Consumer self-evaluation is to take consumers as the research object, collect consumers' feedback on product odor, skin feel, touch, taste and other related characteristics through consumer trials and questionnaire surveys, and then combine the results of questionnaire survey statistics , To evaluate the efficacy of cosmetics. This method can obtain the most intuitive feelings and evaluations of consumers about the product. Through data statistics and analysis, the corresponding efficacy of the product can be directly supported. However, in order to avoid the influence of strong subjectivity on the results, the design of the questionnaire is also relatively high. Requirements.

    Biophysical methods are currently the most widely used and objective technical methods in domestic and foreign industries, including instrumental measurement methods and imaging analysis methods. This method can not only obtain objective and quantitative detection data, but also provide proof for product efficacy claims through intuitive and visual images. At present, with the upgrading of equipment, the excavation of skin science and product action mechanism, and the development of image analysis technology, the non-invasive detection of skin surface parameters to deep skin cell morphology can be achieved through biophysical evaluation methods. The leap from the skin level to the cell level. For example, at the epidermal level, testing equipment or imaging equipment can detect the surface moisture, oil, desquamation, wrinkles and other biophysical indicators of the skin; in the deep skin, it can observe the stratum corneum and dermis morphology, protein, etc. Detection of component structure, detection of skin cell morphology and structure, and quantitative detection of deep skin moisture, protein content, pigment content, and penetration of exogenous components in the skin.


    (2) In vitro method

    In vitro evaluation methods mainly refer to the evaluation of cosmetic efficacy by techniques such as physical and chemical methods, biochemical methods, cell biology methods, and tissue model alternative methods.

    Physical and chemical methods are mainly used in the evaluation of cosmetic moisturizing and sunscreen efficacy. Calculate and characterize the sunscreen effect of the sunscreen product through the absorption and transmittance of ultraviolet rays. This type of method is simple to operate and the results are reproducible.

    Biochemical methods and cell biology methods are mainly applied in the field of anti-aging and anti-oxidation evaluation of cosmetics. With the help of spectroscopic analysis and chemical analysis, the hydroxyl radical scavenging and superoxide anion inhibition capabilities are tested or the tyrosinase inhibition capability is tested. This kind of method is mainly suitable for evaluating the efficacy of cosmetic raw materials. In addition, human or animal cells can be cultured in vitro to construct cell models, and the efficacy of cosmetic raw materials can be characterized by colorimetry or combined with enzyme-linked immunoassay and other technical means. For example, by detecting the ability of cosmetic raw materials to inhibit melanin production of cells and inhibit tyrosinase activity, the whitening effect of raw materials can be evaluated.

    The tissue model method is an important example of the application of bioengineering technology in the field of cosmetic efficacy evaluation. The three-dimensional human skin model constructed by this technology simulates human skin in terms of gene expression, metabolic vitality, tissue structure, etc. It can also construct skin models containing different skin structures according to testing needs, such as in vitro hair follicle culture system, three-dimensional melanin skin model Wait. The application in the evaluation of hair cosmetics/raw materials and the evaluation of whitening efficacy is of great significance. In addition, isolated tissues and organs are also an important basis for the evaluation of cosmetic efficacy. For example, the efficacy evaluation of hair cosmetics usually uses isolated hair as the research object, observes the microstructure of hair fibers through microscopic imaging technology, and detects the ductility, breaking strain, tensile performance, and combing performance of the hair. Evaluate the effects of cosmetics, mechanical damage, dryness, etc. on hair.


    3. Current status of efficacy evaluation of cosmetics at home and abroad

    In recent years, with the continuous development of my country's cosmetics industry, the research on the efficacy evaluation technology of cosmetics has become more and more in-depth, and the gap with international advanced technology has become smaller and smaller.

    In the context of the early start of the cosmetics industry, developed countries such as Europe and the United States have always been in the forefront of the world in the supervision of product efficacy. With the advantages of skin science research and mechanical equipment development technology, the corresponding efficacy evaluation technology and equipment of cosmetics are relatively mature, leading the development of the industry. In terms of non-invasive testing methods for the efficacy of cosmetics, a number of guidance methods and guidelines have been issued, and relevant research results have been published in various industry key journals. For example, EEMCO (European Cosmetics and Other Commodity Effectiveness Evaluation Expert Agency) has issued a number of clinical evaluation technical guidelines for the detection of skin biophysical parameters, including skin color test, skin gloss test, moisture content test, skin Barrier function test, hair product efficacy test, etc., provide support for the product's comprehensive effects such as whitening, moisturizing, and anti-wrinkle. For many years, such methods have been the main basis for reference in the industry. In addition, various countries have successively established standard methods for evaluating the efficacy of sunscreen cosmetics, such as JCIA standard methods and FDA standard methods. Among them, standard methods related to sun protection have also been included in ISO standards.

    Although my country has established a series of method standards for the evaluation of cosmetic efficacy, they are limited to sunscreen and moisturizing products. The standardization of methods still needs to be improved. For example, in 2011, the Ministry of Industry and Information Technology issued my country's first guidelines for cosmetic efficacy evaluation methods, namely, the light industry standard QB/T4256-2011 cosmetic moisturizing efficacy evaluation guidelines. This guide was jointly drafted by the Chinese Academy of Inspection and Quarantine Sciences, Beijing Technology and Business University, and the PLA Air Force General Hospital. It is used to standardize the method of evaluating cosmetic moisturizing efficacy and is the most basic standard referenced in the current cosmetic moisturizing efficacy evaluation. In addition, the method for measuring the SPF value of sunscreen cosmetics, the method for measuring the long-wave ultraviolet protection index (PFA value) of sunscreen cosmetics, and the method for measuring the waterproof performance of sunscreen cosmetics included in my country's "Cosmetics Safety Technical Specifications" (2015 edition) are also the earliest in my country Efficacy evaluation method standard. In 2019, the General Administration of Customs issued the entry-exit inspection and quarantine industry standard "SN/T5150-2019 Sunscreen Cosmetics UVA Photoprotective Effect In Vitro Test Method", which is equivalent to quoting ISO24443, which was formally implemented in May 2020. This standard is an important translation and quotation of my country’s international evaluation standards for cosmetic efficacy evaluation. The release of this standard indicates that my country’s sunscreen cosmetic efficacy evaluation system has achieved a breakthrough in the field of in vitro research. It will also greatly improve the detection efficiency of cosmetics and effectively Cosmetics supervision provides technical support. After oral care products are placed under the management of the cosmetics system, the current health industry standard WS/T3236.1-2010 issued in 2010 is still applicable, mainly stipulating anti-caries, inhibiting dental plaque and/or reducing gum inflammation , Anti-dentin sensitivity and other methods, this set of standard methods has also become an important part of the standardization of my country’s cosmetic efficacy evaluation system.

    In addition, my country's cosmetics companies and related organizations are also actively establishing internal standardized technical methods, which is of great significance for improving my country's cosmetic efficacy evaluation system. For example, Zhejiang Health Products and Cosmetics Industry Association and Proya Cosmetics Co., Ltd. have jointly formulated and issued "T/ZHCA001-2018 Cosmetics Whitening and Freckle Efficacy Test Method", "T/ZHCA002-2018 Cosmetics Oil Control Efficacy Test Method" and "T/ ZHCA003-2018 Cosmetics influence transepidermal moisture loss test method" "T/ZHCA004-2018 Cosmetics influence skin surface pH test method" "T/ZHCA005-2019 cosmetics influence skin elasticity test method" "T/ZHCA006-2019 Cosmetics anti-wrinkle efficacy test method 》And other group standards, the Shanghai Daily Chemical Industry Association has formulated a clinical evaluation method standard for the efficacy of cosmetics in improving eye lines. Although such standards are voluntary standards adopted by the society and are not compulsory, they can play a leading role in market orientation and industry self-discipline in the industry field.


    4. Regulatory requirements for cosmetic efficacy evaluation

    At present, my country's cosmetics industry is showing the characteristics of multimorphic development, and the flexible switching of product sales models, especially the integration of Internet platforms and e-commerce platforms, has brought huge challenges to the supervision of product and raw material traceability. In order to effectively deal with these challenges, a number of cosmetics regulatory policies in my country have undergone major adjustments this year. In the "Regulations on Supervision and Administration of Cosmetics" issued in June 2020, the original classification of "special use cosmetics" and "non-special use cosmetics" was adjusted to "special cosmetics" and "ordinary cosmetics" based on product names and risk classifications. , And clarified the management and management requirements for the registration and filing of each type of product. At the same time, in July 2020, the National Food and Drug Administration issued the "Specifications for Classification of Cosmetics" (draft for comments), which classified cosmetics into 28 categories, including cleansing, makeup remover, moisturizing, and moisturizing, according to their efficacy claims, parts of action, dosage forms, and users. , The classification is more refined. In the "Guiding Principles for the Evaluation of Cosmetic Efficacy Claims (Draft for Comment)", the evaluation principles and standard testing methods for various efficacies are defined. We can see that my country has stricter supervision of cosmetics and more focused supervision.


    V. Outlook

    In our country, cosmetics efficacy evaluation still has a high dependence on instruments and equipment, and very few companies have scientific efficacy evaluation knowledge, complete efficacy testing equipment and standardized evaluation technology. Most companies rely on third-party testing institutions. Carry out strict cosmetic efficacy evaluation. In contrast, when the functional cosmetics of well-known foreign companies enter the Chinese market, they will conduct internal evaluations and compare them with the evaluation results of third-party testing agencies to confirm the consistency of the results of both parties and ensure the reliability of the evaluation results of functional cosmetics . In this regard, there are still some gaps between Chinese cosmetics companies and international companies. But on the other hand, under the impact of the information age, the development of big data and computer technology, the application of artificial intelligence technology in the field of cosmetic efficacy evaluation in my country has also formed my country's unique advantages and characteristics. At present, my country's cosmetics efficacy evaluation has made great progress in the automation and portability of related equipment, and the scientific, comprehensive, and comprehensive efficacy evaluation results have also been greatly improved, which fully reflects the new creativity of my country's cosmetics industry .

    Therefore, in order to promote the overall level of cosmetic efficacy evaluation in my country in the future, it is necessary for cosmetic companies and related practitioners to use the advantages of continuous technological innovation to jointly advance from various perspectives such as equipment, inspection skills, and training of high-quality inspectors to establish a comprehensive The cosmetic efficacy evaluation system promotes the safe and healthy development of my country's functional cosmetics.

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