Tyclopyrazoflor is expected to do very well when it comes to market

Tyclopyrazoflor is a pyridinyl pyrazole pesticide reported and developed by Dow Company (now Corterva) in 2013. Different from the amide group of existing fish nitine insecticides, Tyclopyrazoflor has the characteristics of novel chemical structure, unique mechanism of action, high efficiency and wide spectrum, and is environmentally friendly. According to the published data, Tyclopyrazoflor has the best control effect on Bemisiatabaci, Bemisia tabaci, Rhynchophorus ferrugineus and nightshade aphids. It can be inferred that clopyrazolamine has a broad spectrum insecticidal activity through the patent analysis.

 Introduction of Tyclopyrazoflor

The technical is white or white-like solid, the specific boiling point, density and other physical properties have not been exact data, but it is known that it is dissolved in DMSO (Dimethyl sulfoxide), the solubility in DMSO: 125 mg/mL, and the acidity coefficient (pKa) is 2.55±0.12(Predicted).

Action mechanism of Tyclopyrazoflor

The mechanism of action of Tyclopyrazoflor has not been reported in detail. However, according to known information, Tyclopyrazoflor mainly interferes with the insect's neurotransmission system, causing the insect to act out of order and ultimately kill the pest. 

The structural features of Tyclopyrazoflor include pyridine groups and pyrazole groups, which may bind to specific receptors in the insect body and thus play an insecticidal role. The nitrogen atoms in the pyridine and pyrazole groups may form hydrogen bond interactions with receptors in the insect body, enhancing the activity of the insecticide.

The application of Tyclopyrazoflor

Applications: citrus, grapes, pineapples, bananas, plantains, pears (especially apples and pears), vegetables (especially tomatoes, lettuce, cucumbers, carrots, Onions, garlic and potatoes), cotton, soybeans, coffee, tea, corn and rice, etc 

Target pests: Whitefly family, Gall mite family, Thrips family, aphid pests such as smoke aphid, cotton aphid, peach aphid, Whitefly, citrus rust tick, thrips, bug bug, etc 

Developable dosage form: 200g/L Tyclopyrazoflor SC

The Patent situation of Tyclopyrazoflor

Tyclopyrazoflor 

On March 7, 2013, Dow Yinong filed WO2013162716 to protect the generic compound, and up to now, the patent has been granted in the United States, China, Japan and other countries.

Composition patent 

Dow Agrochem has filed 12 composition patent applications around Tyclopyrazoflor . Through the pvatent analysis of the main compositions, it can be seen that the active components of the composition that Dow requests protection can be mixed with Tyclopyrazoflor basically cover all insecticides commonly used in the current stage. The side reaction showed that it had relatively broad spectrum insecticidal activity.  

Composition patent 

Dow Agrochem has filed 12 composition patent applications around Tyclopyrazoflor . Through the pvatent analysis of the main compositions, it can be seen that the active components of the composition that Dow requests protection can be mixed with Tyclopyrazoflor basically cover all insecticides commonly used in the current stage. The side reaction showed that it had relatively broad spectrum insecticidal activity.