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Home > Chemial News > Food Industry News > Why is the new type of oral beauty material-collagen tripeptide different?

Why is the new type of oral beauty material-collagen tripeptide different?

Echemi 2021-07-19

The big health industry has become the market outlet, and oral beauty is emerging, becoming a new market demand point and a major global consumer trend. GrandViewResearch data shows that the global oral beauty market has reached US$52 billion in 2020 and is expected to grow to US$69 billion in 2026. In the Chinese market, oral cosmetology is also heating up sharply. Among the 618 cosmetics transactions in 2019, the turnover of oral cosmetology products increased by 2266% year-on-year. Among them, products containing "collagen" ingredients are the largest consumer in the oral cosmetology market.


The growing collagen market

Among the many oral cosmetic ingredients, collagen has been far ahead in terms of recognition and usage. According to the Nutrition Business Journal, collagen only accounted for 1% of the beauty dietary supplement market five years ago, and by 2019, this proportion has reached 9%, and it is still increasing. According to the industry analysis report released by Zhiyan Consulting, the size of China's collagen market in 2017 was approximately 2.13 billion yuan, and it is expected that the market size will grow to 4.58 billion yuan by 2024.

Collagen is the most abundant fibrous protein in the human body, accounting for about 25% of the total body protein. It is the main component of skin, bones, cartilage, hair, hands, feet and nails. A number of studies have confirmed that collagen has the dual effects of maintaining skin moisture and regulating skin elasticity. However, some consumers think that oral collagen is an "IQ tax" because they do not feel any obvious changes in their skin after taking it. This is because not all collagen can be effectively absorbed and utilized. The collagen that the skin really needs is actually a type of collagen composed of 3 amino acid molecules, that is, "collagen tripeptide".


What is collagen tripeptide?


Collagen is a triple helix structure composed of about 20 amino acids with Gly-x-y repeating sequences, of which glycine-proline-hydroxyproline (GPH) plays a major role. Glycine is an important amino acid constituting the peptide chain of collagen, which can stabilize the molecular structure of collagen; proline is one of the amino acids composed of collagen, which can promote the production of collagen by the human body; hydroxyproline is a characteristic amino acid of collagen. It can help rebuild collagen in the body and regenerate and renew elastin. It can be seen that GPH, the core component of collagen, can play a role in a real sense.


The collagen tripeptide (CTP) is the smallest structural unit of collagen. It consists of three amino acids (glycine + proline/hydroxyproline + other types of amino acids). It contains a large amount that is essential for collagen synthesis. The iconic ingredient GPH has a fast absorption rate and can be directly absorbed and deposited in the skin, improving skin wrinkles and moisturizing. Compared with collagen and collagen peptide, collagen tripeptide has the following obvious advantages:

 

1) Higher absorption rate


The molecular weight of collagen is very large (100,000~300,000 Daltons), and the human body can hardly digest and absorb it directly; collagen peptides are composed of 30-50 amino acids. After entering the body, they randomly synthesize protein or collagen in various parts of the body, and the absorption rate is also low. Low; and the molecular weight of collagen tripeptide is only 250~1000 Daltons, which can be directly absorbed and utilized by the small intestine quickly and efficiently. Under the premise of taking the same amount, the absorption rate is higher than ordinary collagen peptide, which can reach more than 95%. , 1.5g of collagen tripeptide is equivalent to 9.0g~10.5g of collagen peptide.


2) Higher utilization


Collagen tripeptide has good skin permeability, can be directly transported to skin fibroblasts through blood, and can be absorbed and utilized by skin without decomposition. The GPH in the collagen tripeptide can be targeted to deposit in the skin, stimulate dermal fibroblasts, generate collagen in the skin, and activate the hyaluron synthase 2 (hyaluron synthase 2), and its stable triple helix structure is also It can lock moisture strongly and keep the skin moist and supple at all times, which is equivalent to supplementing collagen and hyaluronic acid at the same time, repairing skin cells and moisturizing and moisturizing, achieving a multiplier beauty effect with half the effort.


3) Higher stability


Collagen tripeptide has the characteristics of colorless, tasteless, pH stability, and temperature stability. Experiments show that the active ingredient GPH is not decomposed by gastric acid and pepsin until 2 hours after the addition of collagen tripeptide, showing its stability Very high.

A large number of clinical and animal experiments have proved that the intake of collagen tripeptide can increase skin moisture content, reduce transepidermal water loss (TELW), increase the collagen content in the skin, and support the skin structure more effectively, inhibiting wrinkles and diminishing The effect of fine lines can also help osteoporosis and joint health.

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