Pediatric OI
Osteogenesis imperfecta is also known as brittle bone disease. It manifests as systemic connective tissue abnormalities. It is characterized by multiple fractures, blue sclera, progressive deafness, tooth changes, joint laxity and skin abnormalities. Genetics are mostly autosomal dominant, and some cases are autosomal recessive. Cases of skipped-generation inheritance have also been reported.
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Site of disease:
bone -
Infectious :
Not contagious -
Frequent population:
This is common in infants and young children with poor calcium absorption. -
Related symptoms:
Loose joint capsule Kyphosis Head enlargement Blue sclera Joint deformity -
Concurrent disease:
Related Drugs
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