46-XY simple gonadal dysgenesis syndrome in children
46-XY simple gonadal digenesis syndrome (simple 46, XY gonadal digenesis syndrome) is Harnden-Stewart syndrome, also known as Swyer syndrome. The symptoms of this disease are that the patient appears to be female, has cord-shaped gonads, has no physical abnormalities other than gonads, and has a karyotype of 46-XY. There is only gonadal dysgenesis without the physical abnormalities of Turner syndrome. In 1993, Lou Liandi et al. pointed out that such cases have a common point, that is, the chromosome karyotype is 45, X/46XY, and their dysgenetic gonads are of different types, and the clinical manifestations are also different. The name "gonadal dysgenesis" was proposed and adopted internationally.
-
Site of disease:
Male reproduction Female reproduction -
Infectious :
Not contagious -
Frequent population:
Children (1-12 years) -
Related symptoms:
No menstrual cramps Clitoral hypertrophy Vulva immaturity Gonadal hypoplasia Breast or nipple development -
Concurrent disease:
Related Drugs
Recombinant human growth hormone injection
Indication: Used for slow growth in children caused by endogenous growth hormone deficiency; for the treatment of severe burns; for growth hormone deficiency caused by established hypothalamic-pituitary disease and significant growth hormone deficiency confirmed by two different growth hormone stimulation tests.
Related Ingredients
-
Somatonorm list
82030-87-3