Progressive supranuclear palsy
Progressive supranuclear palsy (PSP) is a progressive neurodegenerative disease characterized by degeneration of pontine and midbrain neurons and the appearance of neurofibrillary tangles (NFTs) as the main pathological changes. Because the disease has dystonia posture of head hyperextension and eye movement disorders, it is also called oculocervical dystonia. Posey (1904) first reported this disease. In 1963, Richardson, Steele and Olszewski regarded progressive supranuclear palsy as an independent disease with clinical pathology. In 1972, Steele described the clinical pathological characteristics of this disease in detail, also known as Steele-Richardson-Olszewski syndrome. At that time, there were 73 cases of PSP reported in medical literature, including 22 autopsies. There were several cases in almost every major neurological disease center, so PSP is not rare. The main clinical features of this disease are postural instability, movement disorders, vertical supranuclear palsy, pseudobulbar palsy and mild dementia.
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Site of disease:
Brain -
Infectious :
Not contagious -
Frequent population:
Mostly occurs in men aged 51 to 60 -
Related symptoms:
Hallucination Gag reflex Old people move slowly Unsteady gait Fatigue -
Concurrent disease:
Related Drugs
Potassium chloride tablets
Indication: 1. Treatment of hypokalemia caused by various reasons, such as insufficient food intake, vomiting, severe diarrhea, use of potassium-excreting diuretics, hypokalemic familial periodic paralysis, long-term use of glucocorticoids and supplementation of hypertonic glucose, etc. 2. Prevention of hypokalemia When patients have potassium loss, especially if hypokalemia is harmful to patients (such as patients using digitalis drugs), preventive potassium salt supplementation is required, such as eating very little, severe or chronic diarrhea, long-term use of adrenocortical hormones, potassium-losing nephropathy, Bartter syndrome, etc. 3. Digitalis poisoning causes frequent, multifocal premature beats or rapid arrhythmias.
Manufacturer:
Liaoning Haiyi Pharmaceutical Co., Ltd.
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