This product is a formyl derivative of tetrahydrofolate, mainly used for the rescue of high-dose methotrexate and other folic acid antagonists. It is converted into tetrahydrofolate by tetrahydrofolate reductase, which can effectively counteract the toxic reaction caused by methotrexate, but has no obvious effect on the existing methotrexate neurotoxicity.

Activates multiple enzymes (such as sulfhydryl (-SH) enzymes, etc.), promotes the metabolism of sugar, fat and protein; accelerates its excretion by combining sulfhydryl groups with free radicals, reduces the toxic side effects of chemotherapy and radiotherapy; protects the renal tubules from damage by cisplatin; has obvious effects in treating radiation enteritis; reduces tissue damage caused by anemia, poisoning or tissue inflammation and promotes repair; protects liver function, promotes bile acid metabolism, and facilitates the absorption of fat and fat-soluble vitamins (A, D, E, K) in the digestive tract.

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After being rapidly converted into 1alpha;, 25-dihydroxyvitamin VtD3 by the liver, it regulates the balance of calcium and phosphorus in the body, increases intestinal absorption of calcium and phosphorus, promotes bone mineralization, reduces plasma parathyroid hormone levels, reduces bone calcium elimination, relieves bone and muscle pain, and improves intestinal calcium malabsorption associated with osteoporosis caused by menopause, aging, and the use of glucocorticoids.