An important component of coenzymes required for sugar metabolism

Important coenzyme component required for tissue respiration

Component of coenzyme I and II, essential for lipid metabolism, oxidation of tissue respiration

A cofactor for many enzymes, involved in the metabolism of amino acids and fats

Component of coenzyme A, involved in the metabolism of sugar, fat and protein

This product is a diphenylacetic acid ester compound, which has the effects of relieving gastrointestinal smooth muscle spasm and resisting gastric acid secretion. Its mechanism of action is to block postganglionic cholinergic receptors. This product can effectively inhibit gastric juice secretion, relieve the symptoms of peptic ulcer, relieve gastrointestinal spasm, reduce stomach pain, nausea, vomiting and indigestion, and make gastrointestinal function tend to normal.

Participates in bone formation and reconstruction of bone tissue after fracture, as well as muscle contraction, nerve transmission, coagulation mechanism and reduces capillary permeability, etc.

This product is involved in the formation of bones and the reconstruction of bone tissue after fracture, as well as muscle contraction, nerve transmission, coagulation mechanism and reducing the permeability of capillaries.

This product is involved in the formation of bones and the reconstruction of bone tissue after fracture, as well as muscle contraction, nerve transmission, coagulation mechanism and reducing the permeability of capillaries.

This product is involved in the formation of bones and the reconstruction of bone tissue after fracture, as well as muscle contraction, nerve transmission, coagulation mechanism and reducing the permeability of capillaries.

This product belongs to the azole antifungal drug, and it can inhibit the process of Candida albicans transforming from spores to invasive hyphae. This product has a broad-spectrum antifungal activity, and has good antibacterial effects on Epidermophyton, Trichophyton, Aspergillus, Chromatid fungi, Cryptococcus and Candida. It also has certain antibacterial activity against Sporothrix schenckii, Blastomyces dermatitidis, Coccidioides immitis, Histoplasma, etc. This product inhibits the biosynthesis of ergosterol, the main steroid of fungal cell membrane, by interfering with the activity of cytochrome P-450, damaging the fungal cell membrane and changing its permeability, resulting in leakage of important intracellular substances. This product can inhibit the biosynthesis of triglycerides and phospholipids of fungi, inhibit the activity of oxidases and peroxidases, and cause the accumulation of hydrogen peroxide in cells, leading to cell submicrostructure degeneration and cell necrosis.

It is a cell cycle specific drug that inhibits the purine synthesis pathway. Its chemical structure is similar to that of hypoxanthine, so it can competitively inhibit the conversion process of hypoxanthine. After entering the body, this product must be converted into 6-mercaptopurine ribonucleotide by phosphoribosyltransferase in the cell before it becomes active. It has two main action links: (1) It inhibits amidotransferase through negative feedback, thereby preventing the conversion of 1-pyrophosphate-5-phosphoribosyl (PRPP) to 1-amino-5-phosphoribosyl (PRA), interfering with the initial stage of purine nucleotide synthesis. (2) Inhibits the mutual conversion between complex purines, that is, it can inhibit the conversion of inosine nucleotides to adenine nucleotides and inosine nucleotides to xanthine nucleotides and guanine nucleotides. At the same time, this product also inhibits the synthesis of coenzyme I (NAD) and reduces deoxyadenosine triphosphate (dATP) and deoxyguanosine triphosphate (dGTP) necessary for the biosynthesis of DNA, so that tumor cells cannot proliferate. This product is more sensitive to cells in the S proliferation cycle. In addition to inhibiting the synthesis of cell DNA, it also has a mild inhibitory effect on the synthesis of cell RNA. The use of mercaptopurine to treat leukemia often produces drug resistance, which may be due to the appearance of mutant leukemia cell lines in the body, which have lost the ability to convert mercaptopurine into mercaptopurine ribonucleotides.