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Berberine Trimethoprim Capsules

Function and Efficacy

Berberine hydrochloride and trimethoprim have synergistic antibacterial effects. Berberine hydrochloride has inhibitory effects on a variety of Gram-positive and Gram-negative bacteria in vitro, among which hemolytic streptococci, Staphylococcus aureus, Vibrio cholerae, Neisseria meningitidis, Shigella, Salmonella typhi, Corynebacterium diphtheriae, etc. have stronger inhibitory effects. It also has a certain inhibitory effect on amoeba. Trimethoprim mainly interferes with bacterial folate metabolism, selectively inhibits dihydrofolate reductase, and prevents nucleic acid synthesis. Therefore, the antibacterial effect of the two combined is stronger than that of a single drug, and the drug-resistant strains are reduced.

Ingredients

This product is a compound preparation, and its components are: each tablet contains 100 mg of berberine hydrochloride and 50 mg of trimethoprim.

Name Description Content CAS NO. Manufacturer
Berberine hydrochlorideIngredients

It has an inhibitory effect on a variety of Gram-positive and Gram-negative bacteria in vitro, and has a stronger inhibitory effect on hemolytic Streptococcus, Staphylococcus aureus, Vibrio cholerae, Neisseria meningitidis, Shigella, Salmonella typhi, Corynebacterium diphtheriae, etc. It also has a certain inhibitory effect on amoeba.

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633-65-8 46
TrimethoprimIngredients

It mainly interferes with bacterial folate metabolism, selectively inhibits dihydrofolate reductase, and prevents nucleic acid synthesis.

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738-70-5 44

Indication

Gastroenteritis, bacillary dysentery and other intestinal infections caused by sensitive bacteria.

Usage and Dosage

Take 1-3 capsules at a time, 3 times a day.

Adverse Reactions

Nausea, vomiting, drug rash, and diarrhea will disappear after stopping the drug; itching and rash may occur, and occasionally severe exudative erythema multiforme may occur; aseptic meningitis may occasionally occur, with headaches, stiff neck, etc.

Precautions

1. Patients who are allergic to berberine hydrochloride, trimethoprim and sulfonamides are prohibited from using this product. 2. Children with glucose-6-phosphate dehydrogenase deficiency are prohibited from using this product. 3. Newborns and infants under 2 months old are prohibited from using this product.

Storage

Keep away from light and store in airtight container.

Packaging Specification

Berberine hydrochloride 0.1 g, trimethoprim 50 mg

Manufacturer

Zhuhai MidiTech Biopharmaceutical Co., Ltd.

  • Founded in:

    2015-04-07
  • Address:

    1F, Office Building, No. 150 Damen Road, Sanzao Town, Jinwan District, Zhuhai City
  • Tax NO.:

    914404003251811294
  • Registered Funds:

    20 million yuan
  • Website:

  • Email:

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