Methylcobalamin Injection

Pharmacology (1) Methylcobalamin is an endogenous coenzyme B12. It plays an important role as a coenzyme of methionine synthase in the transmethylation reaction of homocysteine to methionine. (2) Methylcobalamin is easily transferred to the organelles of nerve cells, thereby promoting the synthesis of nucleic acids and proteins. Methylcobalamin is more easily transferred into the organelles of rat nerve cells than cyanocobalamin. In experiments on mouse brain cells and spinal cord nerve cells, it participates in the process of synthesizing thymidine from deoxyuridine, promoting the utilization of folic acid and the metabolism of nucleic acids. Moreover, methylcobalamin can promote the synthesis of nucleic acids and proteins in rats more than cobalamin. (3) Promoting intra-axonal transport and axonal regeneration has an important effect on the sitting of diabetic rats caused by streptozotocin.

The main ingredient of this product is methylcobalamin, and its chemical name is: Coα-[α-(5,6-dimethylbenzimidazolyl)]-Coβ-methylcobaltamide.

This product is a red clear liquid.

1. Used for peripheral neuropathy. 2. Treatment of megaloblastic anemia caused by vitamin B12 deficiency.

1. For adults with peripheral neuropathy, take 0.5 mg once a day, 3 times a week, intramuscularly or intravenously. The dosage can be increased or decreased according to age and symptoms. 2. For adults with megaloblastic anemia, take 0.5 mg once a day, 3 times a week, intramuscularly or intravenously. After about two months of administration, 0.16 mg can be given every 1 to 3 months as a maintenance treatment.

1 Serious adverse reactions (frequency unknown) Allergic reactions: May cause allergic reactions such as decreased blood pressure and difficulty breathing. Patients should be closely observed. If such reactions occur, the medication should be discontinued immediately and appropriate measures should be taken. 2 Other adverse reactions (1) Allergic reactions: Rash occurs ((2) Others: Headache, fever (<0.1%): Sweating, pain at the intramuscular injection site, nodules (frequency unknown). If these adverse reactions occur, the medication should be discontinued.

It is contraindicated for those who are allergic to this product or its ingredients.

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: The safety of using this drug in pregnant and lactating women is not yet clear. Precautions for the elderly: Not yet clear.

Not yet clear.

Keep in a dark and airtight place. +24 months.

1ml:0.5mg

24 months.

YANGTZE River Pharmaceutical Group Nanjing Pharmaceutical. Co., Ltd.

• Founded in:

  2001-01-16

• Address:

  No. 9 Xianlin Avenue, Qixia District, Nanjing

• Tax NO.:

  91320192726063334T

• Registered Funds:

  50 million yuan

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