Cefoxitin Sodium for Injection

Cefoxitin Sodium for Injection kills bacteria by inhibiting cell wall synthesis. Due to the structural characteristics of this product, it has a high resistance to beta-lactamase produced by bacteria. The following common clinical Gram-positive, Gram-negative aerobic and anaerobic pathogens are highly sensitive to this product.

The main ingredient of this product is cefoxitin sodium, and its chemical name is 3-hydroxymethyl-7-a-methoxy-8-keto-7[2(2-thiophene)ethylphenolamino]-5-thio-1-azabicyclo-4,2,0-oct-2-ene-acetic anhydride acyl (sodium salt).

It is suitable for the following infections caused by bacteria that are sensitive to this product: 1. Upper and lower respiratory tract infections. 2. Urinary tract infections including uncomplicated gonorrhea. 3. Peritonitis and other intra-abdominal and intra-pelvic infections. 4. Sepsis (including typhoid fever). 5. Gynecological infections. 6. Bone and joint soft tissue infections. 7. Endocarditis. Since this product is effective against anaerobic bacteria and stable against β-lactamase, it is particularly suitable for mixed aerobic and anaerobic infections, as well as infections caused by bacteria that produce β-lactamase and are sensitive to this product.

Intramuscular injection, intravenous injection or intravenous drip. The common dosage for adults is 1-2g/time, once every 6-8 hours. Or adjust the dosage according to the sensitivity of the pathogen and the condition. For patients with renal insufficiency, adjust the dosage according to the creatinine clearance rate. This product is used for intramuscular injection, each gram is dissolved in 2ml of 0.5% lidocaine hydrochloride; for intravenous injection, each gram is dissolved in 10ml of sterile water for injection; for intravenous drip, 1-2g of cefoxitin sodium is dissolved in 50ml or 100ml of normal saline or 5% or 10% glucose solution.

The adverse reactions of this product are mild. The most common local reactions: thrombophlebitis may occur after intravenous injection, and local induration and tenderness may occur after intramuscular injection. In addition, allergic reactions (rash, itching, eosinophilia, fever, dyspnea, etc.), hypotension, diarrhea, nausea, vomiting, leukopenia, thrombocytopenia, anemia, and transient increases in ALT, AST, ALP, LDH, BUN or serum Cr values are occasionally seen.

It is contraindicated in patients who are allergic to cefoxitin and other cephalosporins.

The simultaneous use of cephalosporins and aminoglycosides can increase renal toxicity. At high concentrations, this product can cause a false slight increase in plasma and urine creatinine levels and urine 7-hydroxycortisol levels, which may cause a false positive reaction to urine sugar.

Keep tightly closed in a cool place.

2.0g (calculated as C16H17N3O7S2)

24 months.

Zhe Jiang JuTai Pharmaceutical Co., Ltd.

• Founded in:

  1997-03-19

• Address:

  No. 4, Caihong Road, Xinxin Street, Kecheng District, Quzhou City

• Tax NO.:

  913308001477612189

• Registered Funds:

  128.5934 million yuan

• Email:

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