Adenosine Monophosphate for Injection

This product is an anti-deoxyribonucleic acid (DNA) virus drug. Its pharmacological action is to bind to the viral deoxyribonucleic acid polymerase, reduce its activity and inhibit DNA synthesis. After entering the cell, adenosine monophosphate is phosphorylated to generate adenosine diphosphate (Ara-ADP) and adenosine triphosphate (Ara-ATP). The antiviral activity is mainly caused by adenosine triphosphate (Ara-ATP). Ara-ATP and deoxyadenosine triphosphate (dATP) compete to bind to viral DNAP, thereby inhibiting the activity of the enzyme and the synthesis of viral DNA. At the same time, it inhibits the activity of viral nucleotide reductase and inhibits the synthesis of viral DNA. It can also inhibit the activity of viral DNA terminal deoxynucleotidyl transferase, so that Ara-A penetrates into the viral DNA and connects to the end of the DNA chain 3prime;-OH position, inhibiting the continued synthesis of viral DNA.

The main ingredient of this product is adenosine monophosphate, and its chemical name is: 9 (beta; D arabinofuranosyl) adenine 5-monophosphate. Molecular formula: C10H14N5O7PH2O Molecular weight: 365.26

This product is white or off-white freeze-dried sterilized powder.

Used to treat stomatitis, dermatitis, encephalitis and cytomegalovirus infection caused by herpes virus infection.

Before use, add 2 ml of sterile saline to each bottle and dissolve it, then inject it intramuscularly or slowly intravenously, or follow the doctor's advice. For adults, take 5-10 mg/kg per day according to body weight. Pay close attention to the occurrence of adverse reactions during medication and deal with them in time.

Pain at the injection site may be seen. In rare cases, neuromuscular pain and joint pain may occur, and occasionally thrombocytopenia, leukopenia or bone marrow giant cell increase may occur, which can recover on their own after stopping the drug and are reversible. Symptomatic treatment can be used if necessary. The degree of adverse reactions is positively correlated with the dosage and course of treatment.

It should not be used with calcium-containing infusions. It should not be used with blood, plasma and protein infusions. Allopurinol can increase the toxicity of this product to the nervous system and it should not be used with allopurinol. Using it with interferon can aggravate adverse reactions.

Keep away from light, tightly closed and in a dry place.

0.1 g (calculated as C10H14N507P·H20)

Wuhan Hualong BIO-CHEMICAL Pharmaceutical Co., Ltd.

• Founded in:

  2000-10-10

• Address:

  No. 31, Wuhuan Avenue, Dongxihu District, Wuhan

• Tax NO.:

  91420100724663678X

• Registered Funds:

  40 million yuan

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