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Niacin Tablets

Function and Efficacy

Nicotinic acid is converted into nicotinamide in the body, and then combined with riboadenin to form nicotinamide adenine dinucleotide (coenzyme I) and nicotinamide adenine dinucleotide phosphate (coenzyme II), which are necessary for lipid amino acid, protein, purine metabolism, tissue respiration oxidation and glycogenolysis. Nicotinic acid can reduce the utilization of coenzyme A; by inhibiting the synthesis of very low density lipoprotein (VLDL), it affects the transport of cholesterol in the blood. Large doses can reduce serum cholesterol and triglyceride concentrations. Nicotinic acid has a peripheral vasodilation effect.

Ingredients

The main ingredient of this product is: niacin.

Name Description Content CAS NO. Manufacturer
Nicotinic acidIngredients

Nicotinic acid is converted into nicotinamide in the body, and then combined with riboadenin to form nicotinamide adenine dinucleotide (coenzyme I) and nicotinamide adenine dinucleotide phosphate (coenzyme II), which are necessary for lipid amino acid, protein, purine metabolism, tissue respiration oxidation and glycogenolysis. Nicotinic acid can reduce the utilization of coenzyme A; by inhibiting the synthesis of very low density lipoprotein (VLDL), it affects the transport of cholesterol in the blood. Large doses can reduce serum cholesterol and triglyceride concentrations. Nicotinic acid has a peripheral vasodilation effect.

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59-67-6 15

Appearance

This product is white tablets

Indication

1. Used to prevent and treat niacin deficiency diseases such as pellagra. Also used as a vasodilator to treat hyperlipidemia. 2. Patients who strictly control or select their diet, or receive parenteral nutrition, who lose weight suddenly due to malnutrition, those who are pregnant or breastfeeding, those who take isoniazid, those who are severely addicted to smoking, alcohol, or drugs, all have increased niacin requirements.

Usage and Dosage

Oral: 1. Adults: (1) Pellagra, usual dosage: 50-100 mg each time, 500 mg per day. If there is stomach discomfort, it is advisable to take it with milk or during meals. Generally, 5 mg each of vitamin B1, B2, and B6 are taken at the same time. (2) Anti-hyperlipidemia, start with 100 mg orally, 3 times a day, and increase to 1-2 g each time, 3 times a day after 4-7 days. 2. Children: Pellagra, usual dosage: 25-50 mg each time, 2-3 times a day.

Adverse Reactions

1. Niacin will hardly cause toxic reactions when kidney function is normal. 2. Common reactions of niacin include: feeling warm, redness of the skin, especially on the face and neck, and headache. 3. Large amounts of niacin can cause diarrhea, dizziness, fatigue, dry skin, itching, dry eyes, nausea, vomiting, stomach pain, etc. 4. Occasionally, large amounts of niacin can cause hyperglycemia, hyperuricemia, arrhythmia, and hepatotoxic reactions. 5. Generally, after taking niacin for 2 weeks, vasodilation and gastrointestinal discomfort can gradually adapt, and gradually increasing the dosage can avoid the above reactions. If there is severe skin flushing, itching, and gastrointestinal discomfort, the dosage should be reduced.

Precautions

(1) Those who are allergic to this drug. (2) Those with active peptic ulcer or arterial bleeding. (3) Those with unexplained elevated aminotransferase or active liver disease.

Drug Interactions

1. Isoniazid can prevent niacin from binding to coenzyme I and cause niacin deficiency, so it is advisable to supplement niacin or niacinamide in appropriate amounts when taking isoniazid. 2. Niacin and vasodilators (such as guanethidine and other antihypertensive drugs) should not be used together. 3. If used with other drugs at the same time, drug interactions may occur. Please consult a doctor or pharmacist for details.

Storage

Sealed storage

Packaging Specification

0.1g

Manufacturer

Linfen Baozhu Pharmaceutical Co., Ltd.

  • Founded in:

    2003-11-21
  • Address:

    Pharmaceutical Industry Zone, Light Industry Park, Yaodu Industrial Park, Linfen City, Shanxi Province
  • Tax NO.:

    91141000754091076G
  • Registered Funds:

    12 million yuan
  • Website:

  • Email:

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