Cefoxitin Sodium for Injection

Cefoxitin Sodium for Injection kills bacteria by inhibiting cell wall synthesis. Due to the structural characteristics of this product, it has a high resistance to beta-lactamase produced by bacteria. The following common clinical Gram-positive, Gram-negative aerobic and anaerobic pathogens are highly sensitive to this product.

The main ingredient of this product is cefoxitin sodium, and its chemical name is 3-hydroxymethyl-7-a-methoxy-8-keto-7[2(2-thiophene)ethylphenolamino]-5-thio-1-azabicyclo-4,2,0-oct-2-ene-acetic anhydride acyl (sodium salt).

Cefuroxime sodium is mainly used clinically for the following infections caused by sensitive bacteria: 1. Respiratory tract infections; 2. Urinary and reproductive system infections; 3. Intra-abdominal infections (including peritonitis and cholangitis); 4. Infections in bones, joints, skin and soft tissues; 5. Sepsis.

Intramuscular injection, intravenous injection or intravenous drip. The common dosage for adults is 1-2g/time, once every 6-8 hours. Or adjust the dosage according to the sensitivity of the pathogen and the condition. For patients with renal insufficiency, adjust the dosage according to the creatinine clearance rate. This product is used for intramuscular injection, each gram is dissolved in 2ml of 0.5% lidocaine hydrochloride; for intravenous injection, each gram is dissolved in 10ml of sterile water for injection; for intravenous drip, 1-2g of cefoxitin sodium is dissolved in 50ml or 100ml of normal saline or 5% or 10% glucose solution.

The adverse reactions of this product are mild. The most common local reactions: thrombophlebitis may occur after intravenous injection, and local induration and tenderness may occur after intramuscular injection. In addition, allergic reactions (rash, itching, eosinophilia, fever, dyspnea, etc.), hypotension, diarrhea, nausea, vomiting, leukopenia, thrombocytopenia, anemia, and transient increases in ALT, AST, ALP, LDH, BUN or serum Cr values are occasionally seen.

1. It is contraindicated for patients who are allergic to cefoxitin and other cephalosporins; 2. It should be used with caution in elderly and frail patients; 3. It should be used with caution in premature infants and newborns; 4. It should be used with caution in pregnant and lactating women.

Precautions for children: Use with caution in premature infants and newborns. Precautions for pregnancy and lactation: Use with caution in pregnant and lactating women. Precautions for the elderly: Use with caution in elderly and frail patients.

The simultaneous use of cephalosporins and aminoglycosides can increase renal toxicity. At high concentrations, this product can cause a false slight increase in plasma and urine creatinine levels and urine 7-hydroxycortisol levels, which may cause a false positive reaction to urine sugar.

Keep tightly closed in a cool place.

Calculated as C16H17N3O7S2 1.0g

24 months.

Hunan Hengsheng Pharmaceutical Co., Ltd.

• Founded in:

  2001-09-17

• Address:

  Hengsheng Road, Xidu Economic and Technological Development Zone, Hengyang, Hunan Province

• Tax NO.:

  91430400730523233Y

• Registered Funds:

  100 million yuan

• Email:

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