Cefditoren Pivoxil Tablets

The mechanism of action of this product is to block the synthesis of bacterial cell walls. Cefditoren has a strong binding affinity with 3, 1A, and 1Bs in penicillin-binding protein (PBP), thus exerting a bactericidal effect. Cefditoren has antibacterial effects on both Gram-positive and Gram-negative bacteria. In particular, it has a strong antibacterial effect on Streptococcus and Pneumococcus among Gram-positive bacteria, Escherichia coli, Klebsiella, gonococci, Haemophilus influenzae and anaerobic Streptococcus pyogenes among Gram-negative bacteria. It has a good antibacterial effect on Serratia, indole-positive Proteus, Enterobacter, Citrobacter, etc., which are not sensitive to previous oral cephalosporin preparations (Pioneer IV, Cefaclor, etc.). Cefditoren is stable to beta-lactamase produced by various bacteria, so it is effective against strains that produce beta-lactamase.

Cefterampivoxil.

The following infectious diseases caused by sensitive bacteria such as Streptococcus (except Enterococcus), Pneumococcus, Streptococcus pyogenes, Gonorrhea, Escherichia coli, Citrobacter, Klebsiella, Enterobacter, Serratia, Proteus, Haemophilus influenzae, etc.: pharyngitis (pharyngitis, laryngitis), tonsillitis (peritonsillitis, peritonsillar abscess), acute bronchitis, pneumonia, chronic bronchitis, diffuse bronchiolitis, bronchiectasis (when infected), repeated infection of chronic respiratory diseases; pyelonephritis, cystitis; gonococcal urethritis; adnexitis, endometritis, intrauterine infection, Bartholinitis, Bartholin gland abscess; otitis media, sinusitis; periodontitis, pericoronitis, palatitis.

Pharyngitis (pharyngitis, laryngitis), tonsillitis (peritonsillitis, peritonsillar abscess), acute bronchitis, pyelonephritis, cystitis, adnexitis, endometritis, intrauterine infection, Bartholinitis, Bartholin gland abscess: the regular adult dose is 50-100 mg three times a day, taken orally after meals. Chronic bronchitis, diffuse bronchiolitis, bronchiectasis (infection), repeated infection of chronic respiratory diseases, pneumonia, otitis media, sinusitis, gonococcal urethritis, periodontitis, pericoronitis, palatitis: the regular adult dose is 100-200 mg three times a day, taken orally after meals. For patients with severe renal insufficiency, medication should be taken with caution and the dose and interval should be adjusted appropriately.

Usually rare and mild. General adverse reactions are mainly diarrhea, rash, loss of appetite, stomach discomfort, increased GTP, increased GOP, and eosinophilia. Serious adverse reactions: The following serious adverse reactions may be observed, but the frequency is unknown. Shock, rapid allergic reaction (dyspnea, etc.). Toxic epidermal necrosis syndrome-Stevens-Johnson syndrome. Acute renal failure. Pseudomembranous colitis. When the above serious adverse reactions occur, the drug should be discontinued immediately and properly handled. Similar drugs (cephalosporin antibiotics) may have the following serious adverse reactions: hemolytic anemia. Interstitial pneumonia and pulmonary interstitial edema accompanied by fever, cough, dyspnea, abnormal chest X-ray, eosinophilia, etc. Other adverse reactions include: allergic reactions-rash, erythema, joint pain (incidence 0.1-2% or unknown). Urticaria, itching, fever, edema, lymphadenopathy (incidence less than 0.1%). Blood system - eosinophilia (incidence 0.1-2% or unknown). Granulocytopenia, thrombocytopenia (incidence less than 0.1%). Liver - increased GOT, GPT, jaundice (incidence 0.1-2% or unknown). Al-P, LDH increased (incidence less than 0.1%). Digestive system - diarrhea, soft stools, nausea, vomiting, loss of appetite, stomach discomfort (incidence 0.1-2% or unknown). Abdominal distension, heartburn, abdominal pain (incidence less than 0.1%). Dysbacteriosis - Candida infection (incidence 0.1-2% or unknown), stomatitis (incidence less than 0.1%). Vitamin deficiency - vitamin K deficiency (hypoprothrombinemia, bleeding tendency, etc.), vitamin B deficiency (glossitis, stomatitis, loss of appetite, neuritis, etc.) (incidence 0.1-2% or unknown). CPK increased (incidence 0.1-2% or unknown). Headache, dizziness, and general fatigue (incidence less than 0.1%).

Patients who are allergic to cefditoren or the ingredients of this drug.

Cephalosporins can inhibit intestinal flora and lead to a decrease in vitamin K synthesis. It is recommended that patients with malnutrition or severe illness take vitamin K at the same time as long-term use of anticoagulants, coumarins, 13-indandione derivatives, heparin, thrombolytics and other drugs.

Store at room temperature, moisture-proof. Store away from light after opening the aluminum-plastic packaging. Valid for 3 years.

50 mg

24 months