Cefotezol Sodium for Injection

Ceftezole sodium is a semi-synthetic cephalosporin derivative, and its mechanism of action is to exert antibacterial activity by inhibiting the synthesis of bacterial cell walls. Ceftezole sodium has antibacterial activity against the following bacteria: 1. Aerobic Gram-positive bacteria: Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes. 2. Aerobic Gram-negative bacteria: Escherichia coli, Klebsiella pneumoniae, Proteus.

The main ingredient of this product is ceftriaxone sodium, and its chemical name is (6R,7R)-3-〔[(1,3,4-thiazol-2-yl)thio]methyl〕-7-[(1H-4-oxazol-1-yl)acetylamino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt.

This product is white to light yellow crystalline powder, odorless and hygroscopic.

Sepsis, pneumonia, bronchitis, bronchiectasis (in case of infection), secondary infection of chronic respiratory diseases, lung abscess, peritonitis, pyelonephritis, cystitis, urethritis.

Adults take 0.5g~2g (2~8 vials) at a time, twice a day, intravenously or intramuscularly. For severe infections, the dose can be appropriately increased as prescribed by the doctor. Preparation of injection: 1. Intravenous injection: Dissolve in water for injection, normal saline or 5% glucose injection, and inject slowly. 2. Intravenous drip: Dissolve in normal saline or 5% glucose injection. 3. Intramuscular injection: Dissolve in 0.5% lidocaine hydrochloride injection. If the injection becomes turbid due to temperature reasons when it is dissolved, it can be heated to clarify it before use. It is best to use it immediately after dissolution. If it needs to be stored, it should be stored in a cool place (below 15°C) to prevent precipitation, but it must be used within 72 hours.

1. Shock: Shock rarely occurs, and close observation is required. If any symptoms related to the use of this product occur, such as discomfort, abnormal sensation in the mouth, asthma, dizziness, sudden abnormal bowel movements, tinnitus, sweating, etc., the drug should be stopped immediately and necessary treatment should be given. 2. A few have allergic reactions, such as rash, urticaria, skin redness, itching, fever, etc., which disappear when the drug is stopped. 3. Severe renal function abnormalities are rare, and blood creatinine is occasionally increased. If abnormalities are found, the drug should be stopped immediately and necessary treatment should be given. 4. Granulocytopenia, leukopenia, eosinophilia, thrombocytopenia, etc. are rare. When the above abnormalities are found, the drug should be stopped. 5. GOT, GPT, and alkaline phosphatase increase are rare. When the above abnormalities occur, the drug should be stopped immediately. 6. Gastrointestinal reactions, such as nausea, vomiting, diarrhea, etc. are rare, and pseudomembranous colitis is rare. When abdominal pain and diarrhea occur, the drug should be stopped immediately. 7. Dysbacteriosis: Candida infection rarely occurs. 8. Vitamin deficiency: Vitamin K deficiency and B vitamin deficiency are rare. 9. Interstitial pneumonia, toxic fever, cough, dyspnea, abnormal chest X-ray, eosinophilia are rare. When the above symptoms occur, the drug should be discontinued and appropriate treatment should be given. 10. Others: Headache, general malaise, fever, superficial glossitis are rare.

1. Patients with a history of allergy to this product or cephalosporin antibiotics. 2. Patients with a history of allergy to lidocaine or acylanilide local anesthetics (this contraindication is limited to patients receiving intramuscular injections).

1 Do not use with nephrotoxic drugs, including strong diuretics furosemide, ethacrynic acid, bumetanide and aminoglycoside antibiotics. 2 This product is contraindicated with the following drugs: chlortetracycline hydrochloride, aminophylline, calcium chloride, calcium gluconate, diphenhydramine hydrochloride and other antihistamines, norepinephrine, metaraminol, phenytoin sodium, vitamin B group, vitamin C, etc.

Seal and store in a cool, dark and dry place. Validity period: two years

Calculated as C13H12N8O4S3 0.75g

Tianjin Shin Poong Pharmaceutical Co., Ltd.

• Founded in:

  1995-02-24

• Address:

  No. 8, Muning Road, Tianjin Economic and Technological Development Zone

• Tax NO.:

  91120116600587415N

• Registered Funds:

  $9 million

• Email:

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