Cephalexin and Trimethoprim Capsules
Function and Efficacy
Cephalexin is a first-generation cephalosporin with an antibacterial spectrum similar to that of cephalothin, but its antibacterial activity is poorer than that of the latter. Except for Enterococcus and methicillin-resistant Staphylococci, most strains of Streptococcus pneumoniae, hemolytic Streptococcus, and Staphylococci that produce or do not produce penicillinase are sensitive to this product. This product has a good antibacterial effect on Neisseria, but Haemophilus influenzae is less sensitive to this product. This product has a certain antibacterial effect on some Escherichia coli, Proteus mirabilis, Salmonella and Shigella. The remaining Enterobacteriaceae, Acinetobacter, Pseudomonas aeruginosa, and Bacteroides fragilis are resistant to this product. Fusobacterium and Veillonella are generally sensitive to this product, and anaerobic Gram-positive cocci are moderately sensitive to this product. Trimethoprim is an antibacterial agent, and its mechanism of action is to interfere with bacterial folate metabolism.
Ingredients
This product is a compound preparation, each tablet containing 0.125g of cephalexin and 0.025g of trimethoprim.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| CephalexinIngredients |
Cephalexin is a first-generation cephalosporin. It is sensitive to most strains of Streptococcus pneumoniae, hemolytic Streptococcus, and Staphylococcus aureus that produces or does not produce penicillinase. It has a good antibacterial effect on Neisseria and has a certain antibacterial effect on some Escherichia coli, Proteus mirabilis, Salmonella, and Shigella. The remaining Enterobacteriaceae, Acinetobacter, Pseudomonas aeruginosa, and Bacteroides fragilis are all resistant to it. Fusobacterium and Veillonella are generally sensitive to it, and anaerobic Gram-positive cocci are moderately sensitive to it. More |
15686-71-2 | 33 | |
| TrimethoprimIngredients |
Trimethoprim is an antibacterial agent that acts by interfering with bacterial folate metabolism. More |
738-70-5 | 44 |
Appearance
This product is a capsule, and the contents are white or off-white granules and powder.
Indication
Used for infections caused by penicillin-resistant Staphylococci, Streptococci, Pneumococci, Escherichia coli, etc.
Usage and Dosage
Oral administration: 1~2 capsules at a time, 4 times a day. Children can take a smaller dose or follow the doctor's advice.
Adverse Reactions
1. Nausea, vomiting, diarrhea and abdominal discomfort are more common. 2. Allergic reactions such as rash and drug fever. Rarely, anaphylactic shock may occur. 3. Neurological reactions such as dizziness, diplopia, tinnitus, convulsions, etc. 4. Renal damage may occur occasionally during the use of this product. 5. Occasionally, patients have elevated serum aminotransferase and positive Coombs test. Hemolytic anemia is rare, and neutropenia and pseudomembranous colitis have also been reported. 6. Trimethoprim's interference with folic acid metabolism can produce adverse reactions in the blood system, such as leukopenia, thrombocytopenia or methemoglobin anemia. Generally, leukopenia and thrombocytopenia are mild, and can be recovered by stopping the drug in time. Folic acid preparations can also be added.
Precautions
1. Patients who are allergic to cephalosporins or penicillin are prohibited from using this product. 2. Patients who are allergic to trimethoprim are prohibited from using this product. 3. Neonates and premature infants are prohibited from using this product. 4. Patients with severe liver and kidney diseases are prohibited from using this product. 5. Patients with blood diseases are prohibited from using this product.
Special Population Medication
Precautions for children: Forbidden for newborns and premature infants. Precautions for pregnancy and lactation: Forbidden for newborns and premature infants.
Drug Interactions
Not yet clear
Storage
Keep away from light and store in sealed container.
Packaging Specification
Cephalexin 62.5mg, trimethoprim 12.5mg
Manufacturer
Jilin Aodong Pharmaceutical Industry Group Yanji Co., Ltd.
-
Founded in:
1998-09-24 -
Address:
No. 389, Changbai Road, High-tech Development Zone, Yanji City, Jilin Province -
Tax NO.:
912224017022762985 -
Registered Funds:
161.526808 yuan -
Email: