Halcinonide Cream
Function and Efficacy
Efficacy of this product: 1. Anti-inflammatory effect. This product is a topical medication and a highly effective fluorinated and chlorinated corticosteroid with anti-inflammatory, anti-pruritic and vasoconstrictive effects. This product replaces the 21st hydroxyl group with a chlorine atom on the skeleton of triamcinolone. The anti-inflammatory potency multiple determined by the vasoconstriction test is 360. There is evidence that the intensity of the vasoconstriction test is consistent with the efficacy. Its anti-inflammatory and antipruritic mechanism of action is to increase the reactivity of β receptors to catecholamine, increase the production of CAMP by activating adenylate cyclase, and reduce the destruction of CAMP by inhibiting phosphoethylesterase, resulting in an increase in the annual concentration of cAMP in cells and inhibiting the release of histamine. The effect of this product in inhibiting the proliferation of granulomas in rats and mice is similar to that of dexamethasone. Mice induced by formaldehyde
Ingredients
The main ingredients of this product and their chemical names are: Halcinonide (clofosinolone, halcinonide), 16α, 17-[(1-methylethylidene)bis(oxy)]-11β-hydroxy-21-chloro-9-fluoropregnane-4-ene-3,20-dione.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| HalcinonideIngredients |
A highly effective fluorinated and chlorinated corticosteroid with anti-inflammatory, antipruritic and vasoconstrictive effects. It increases the reactivity of β receptors to catecholamine, activates adenylate cyclase to increase CAMP production, and inhibits phosphoethylesterase to reduce CAMP destruction, resulting in an increase in cAMP concentration in cells and inhibiting the release of histamine. Its effect in inhibiting the proliferation of granulomas in rats and mice is similar to that of dexamethasone. More |
3093-35-4 | 9 |
Appearance
This product is a white cream with an emulsion base
Indication
This product is used for contact eczema, atopic dermatitis, neurodermatitis, small-area psoriasis, lichen sclerosus atrophicus, lichen planus, discoid lupus erythematosus, seborrheic dermatitis (non-facial) hypertrophic scars.
Usage and Dosage
Apply to the affected area once in the morning and evening.
Adverse Reactions
1. A small number of patients experience burning sensation, stinging, and temporary itching at the site of application. Long-term use may cause dilation of skin capillaries (especially on the face), skin atrophy, and atrophic striae (prone to adolescents). Skin atrophy may be followed by purpura, ecchymosis, skin fragility, hirsutism, folliculitis, miliary papules, skin depigmentation, and delayed ulcer healing. The packing method is prone to secondary fungal infection in skin folds. 2. When absorbed through the skin for a long time, systemic adverse reactions may occur (see precautions).
Precautions
1. Those who are allergic to the drug. 2. Primary skin lesions caused by bacteria, fungi, viruses and parasites. 3. Ulcerative lesions. 4. Acne and rosacea. 5. Use on the eyelids (risk of causing glaucoma). 6. Exudative skin diseases. 7. Not suitable for use on the face.
Drug Interactions
If you are using other medicines, you should consult your physician or pharmacist before using this product.
Storage
Store tightly closed at room temperature.
Packaging Specification
10g:10mg
Manufacturer
Tangshan Likang Pharmaceutical Co., Ltd.
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Founded in:
1999-12-22 -
Address:
Tangshan Guye District Linxi Hexilixi -
Tax NO.:
9113020072161079XW -
Registered Funds:
12.9 million yuan -
Email: